Formulation of Cinchona Extract (Cinchona Succirubra) Cream and Its Safety as Hair Fertilizer

The study formulated a cinchona extract cream with a 20% dosage, demonstrating its potential as a hair growth enhancer. The cream showed good physical stability with a pH of 6.48, adhesion of 1.16, spreadability of 4.99, and viscosity of 3067. In tests on guinea pigs, the cream increased hair length by 13.54% to 62.14% compared to the normal control and 10.10% to 49.17% compared to the negative control. Hair mass was 122.91% heavier than the normal control and 104.48% of the negative control. The cream was non-irritant in acute dermal irritation tests on rabbits, indicating its safety for use.