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This study evaluated a 20% cinchona extract cream and found it increased hair growth length and mass in guinea pigs, demonstrated good physical stability, and did not irritate rabbit skin.

This study found that Manganese PCA, Cinchona succirubra, and Leontopodium alpinum extracts may promote hair growth by enhancing VEGF secretion and activating the Wnt/b-catenin pathway in Human Hair Follicle Dermal Papilla Cells.

In a study on hair loss treatment, researchers found that a serum containing Cinchona succirubra extract and caffeine improved hair density and reduced hair loss in individuals with acute telogen effluvium after 16 weeks of use, with significant improvements observable after just 4 weeks.

In this clinical study, a serum containing Cinchona succirubra extract and Caffeine significantly improved hair growth and reduced hair loss in subjects with acute telogen effluvium.

This study found that the F6 formulation of a hair tonic containing EDS and ATG extracts produced the most significant hair growth in rabbits, without causing skin irritation and remaining stable throughout the observation period.