7 citations,
January 2016 in “Experimental and Clinical Endocrinology & Diabetes” Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.
5 citations,
July 2016 in “Canadian Urological Association journal” Hair loss in women linked to higher sexual dysfunction risk.
January 2024 in “Frontiers in endocrinology” Treating early puberty with hormone therapy may increase the risk of polycystic ovary syndrome in adults.
59 citations,
October 2012 in “Pharmaceutical Research” Squalene-based carriers improve delivery of a treatment to hair follicles for alopecia areata.
December 2005 in “Endocrine-related cancer” A woman's adrenal tumor disappeared after treatment with cyproterone acetate.
2 citations,
August 2016 in “Surgery for obesity and related diseases” TSH is not reliable for detecting hypothyroidism after bariatric surgery; FT3/rT3 ratio is better.
January 2018 in “Journal of translational science” Eating alfalfa sprouts every day can raise testosterone levels in middle-aged men, but broccoli sprouts don't have this effect.
32 citations,
July 1999 in “Fertility and Sterility” Finasteride and flutamide both reduce hair growth, but finasteride has fewer side effects.
12 citations,
December 2002 in “Fertility and Sterility” Spironolactone plus finasteride works better for treating hirsutism.
63 citations,
March 2001 in “Fertility and Sterility” Diane 35 plus finasteride is more effective for treating hirsutism.
50 citations,
May 2000 in “Fertility and Sterility” Flutamide reduces hair growth better but has more side effects.
47 citations,
March 2004 in “European journal of endocrinology” Spironolactone plus finasteride reduces hirsutism more effectively.
11 citations,
January 2016 in “The Journal of Sexual Medicine” Young women with nonclassic congenital adrenal hyperplasia may experience worse sexual function and mild depression compared to healthy women.
4 citations,
January 2017 in “Acta Endocrinologica” Finasteride and metformin both help treat PCOS, but using them together works best.
1 citations,
July 2019 in “The journal of applied laboratory medicine” Venous catheterization may help diagnose the cause of female hyperandrogenism when imaging is unclear.
May 2023 in “The journal of sexual medicine” Ovarian Hyperthecosis caused hypersexuality in an older woman and was successfully treated with surgery.
352 citations,
January 2006 in “The Journal of Clinical Endocrinology and Metabolism” Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.
75 citations,
November 1996 in “Fertility and Sterility” Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.
51 citations,
October 2002 in “European journal of endocrinology” Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.
50 citations,
April 2000 in “Fertility and Sterility” Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.
49 citations,
June 1998 in “Journal of Endocrinological Investigation” Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.
38 citations,
May 2006 in “Archives of Gynecology and Obstetrics” Women with only irregular periods or excess hair have a better hormone profile than those with full PCOS, but both groups are similar, indicating a need for better PCOS diagnosis methods.
38 citations,
February 2005 in “The journal of sexual medicine” The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
38 citations,
January 1997 in “Gynecological Endocrinology” Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.
24 citations,
March 2017 in “Archives of Gynecology and Obstetrics” The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
18 citations,
January 2009 in “Journal of Endocrinological Investigation” Flutamide works better than finasteride for hirsutism, and combining both is slightly better but not much.
13 citations,
June 2018 in “Journal of Womens Health” Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.
10 citations,
September 2015 in “Gynecological Endocrinology” Both treatments reduced excessive hair growth in PCOS, but there was no difference in weight, hair score, hormone levels, or insulin resistance.
4 citations,
January 1987 in “Annual reports in medicinal chemistry” New treatments for skin diseases are more effective and patient-friendly, but many still lack a cure.
2 citations,
July 2012 in “Journal of Pediatric and Adolescent Gynecology” A 12-year-old girl with very high testosterone and insulin resistance improved with birth control pills, suggesting PCOS can cause high testosterone without tumors.