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Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

Asian patients with Frontal Fibrosing Alopecia often lose eyebrow hair and respond well to combined antiandrogen or antimalarial and topical treatments.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

CBD can either reduce inflammation and not affect hair growth at low levels or inhibit hair growth at high levels.

Finasteride affects brain stress and enzyme activity differently in various regions, possibly helping with liver-related brain issues.

The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.

Fat cells help recruit healing cells and build skin structure during wound healing.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Pharmacists should interpret lab data and perform physical exams to improve patient care.

Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.

Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

Fat-related cells are important for initiating hair growth.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

MED1 affects skin wound healing differently in young and old mice.

UV-B light increases inflammation-related substances in acne-related skin cells.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.