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Skin fat helps with body temperature control and has other active roles in health.

Lower SHBG levels may increase the risk of PCOS.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Type 2 diabetes, bacterial scalp infections, and tight hairstyles like braids and weaves are linked to a higher risk of a scarring hair loss condition in African American women.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Oral tofacitinib can significantly improve recalcitrant lichen planopilaris.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Lamins are vital for cell survival, organ development, and preventing premature aging.

The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.