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Topical calcineurin inhibitors, especially 0.1% tacrolimus ointment, are effective and well-tolerated for treating cutaneous lupus erythematosus but require more research for standard treatment guidelines.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

Hirsutism in women is often due to hormone sensitivity and has significant psychological effects.

Hirsutism causes significant psychological distress in women.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Finasteride can cause sexual dysfunction and depression, which may persist and require hormonal treatment.

A five-month-old boy with Omenn syndrome successfully recovered after a stem cell transplant with reduced intensity conditioning.

Effective symptom management in IBD improves quality of life and prevents complications.

H-1 antihistamines may help with various skin conditions, but more research is needed to confirm their effectiveness.

Blood removal and birth control pills both helped with hormone levels in women with PCOS, but birth control was better for regular periods and blood removal had fewer side effects.

Skin changes like hair loss, white patches, and nail changes are common in children after bone marrow transplants, often linked to chronic rejection.

Fluoxetine's effectiveness as an antidepressant in mice depends on a specific protein activity and a 5-minute pretest.

Lower vaspin levels in the blood may indicate a better response to fertility treatment in women with PCOS.

Home-use lasers and IPL devices are unlikely to directly cause paradoxical hair growth; it may be linked to inflammation or hormonal issues.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

Testosterone is crucial for development, growth, and various body functions in mammals.

Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Certain immune cells are more common on the top of the head and might help predict or treat common hair loss.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Green tea component EGCG helps keep rat skin grafts viable longer.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

A 23-year-old woman with Hashimoto’s thyroiditis improved significantly after a 15-month integrative treatment plan.

Nursing women in the West Bank with higher income and non-smoking habits have higher blood zinc levels.

Hirsutism, excessive hair growth in women, is often caused by PCOS and can be managed with medication and personalized treatment plans.

Adding licorice gel to laser treatment is more effective for reducing facial hair than laser alone.

Ciproterone acetate improves hair regrowth and acne in most female patients.