Hirsuties

    March 2001 in “ Clinics in dermatology ”
    R.P.R. Dawber, Rodney Sinclair
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    TLDR Hirsutism in women is often due to hormone sensitivity and has significant psychological effects.
    This review article from 2001 examined the causes, physical assessment, treatment, and pharmacological therapies for hirsutism, a condition where females develop terminal hair in patterns typical of adult males. It highlighted the significant psychosocial impact and potential underlying endocrine abnormalities associated with hirsutism. The condition results from the sensitization of androgen-dependent hair follicles, converting vellus hair to terminal hair. Over 70% of women with androgen excess exhibited hirsutism, though not all cases were linked to detectable androgen excess, suggesting increased end-organ sensitivity to androgens. The article also discussed future developments in the assessment and treatment of hirsutism.
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