Non-Malignant Late Cutaneous Changes After Allogeneic Hematopoietic Stem Cell Transplant in Children

March 2018 in “ Journal of The American Academy of Dermatology ”

Jennifer T. Huang, James Song, Elena B. Hawryluk, Wendy B. London, Deliang Guo, Makuteswaran Sridharan, David E. Fisher, Leslie Lehmann, Christine Duncan

alopecia vitiligo psoriasis sebopsoriasis nail changes chronic graft-versus-host disease cGVHD busulfan conditioning male pattern baldness hair loss baldness

Studysummary This study found that pediatric HSCT recipients, especially those with chronic graft-versus-host disease, are at risk for developing various nonmalignant late cutaneous changes such as vitiligo, psoriasis, alopecia, and nail changes.

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research Permanent Diffuse Alopecia After Hematopoietic Stem Cell Transplantation in Childhood

16 citations , March 2017 in “Bone Marrow Transplantation”

In this study, permanent alopecia after haematopoietic stem cell transplantation was found in 16% of patients and was significantly associated with conditioning regimens involving busulphan.

High Frequency of Cutaneous Manifestations Including Vitiligo and Alopecia Areata in a Prospective Cohort of Patients with Chronic Graft-Versus-Host Disease

research High Frequency of Cutaneous Manifestations Including Vitiligo and Alopecia Areata in a Prospective Cohort of Patients with Chronic Graft-Versus-Host Disease

17 citations , June 2016 in “Croatian Medical Journal”

In this study, vitiligo and alopecia areata were more common among patients with chronic graft-vs-host disease than previously reported, linked to higher NIH skin scores and greater immunosuppressive treatment.

research Risk Factors and Characterization of Vitiligo and Alopecia Areata in Patients With Chronic Graft-Versus-Host Disease

27 citations , September 2014 in “JAMA dermatology”

In this NIH study, female donor to male recipient sex mismatch was significantly associated with the development of vitiligo and/or alopecia areata in patients with chronic graft-vs-host disease.