research Evaluation of the Efficacy of Topical Minoxidil in the Treatment of Male Androgenetic Alopecia
Topical minoxidil 5% effectively improves hair density and width in men with androgenetic alopecia.
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research A Case of Cicatricial Female Pattern Hair Loss
A 36-year-old woman with worsening hair loss over 10 years was treated with various medications, and after six months, her hair loss did not worsen significantly.
research Clinical, Trichoscopic and Immunohistochemical Evaluation of Autologous Adipose-Derived Adult Stem Cell Injection in the Treatment of Female Pattern Hair Loss
ADSC injections improve hair density, thickness, and reduce inflammation in female pattern hair loss.
research The Inflammatory Aspect of Male and Female Pattern Hair Loss
Inflammation plays a key role in male and female pattern hair loss, and focusing on this could help develop better treatments.
research Frontal Fibrosing Alopecia Presenting as Androgenetic Alopecia in an African American Woman
Frontal fibrosing alopecia can be misdiagnosed as androgenetic alopecia in African American women.
research Topical Diclofenac 3% Gel for Actinic Keratosis May Induce Terminal Hair in Male Androgenetic Alopecia: A Report of Three Cases
Using a gel called Diclofenac can potentially cause hair to grow back in bald spots in older men.
research Trichoscopic Criteria of Female Pattern Hair Loss
Female hair loss can be diagnosed using specific trichoscopy criteria.
research Improvement of Hair Graying During Treatment of Male Pattern Hair Loss Using 1,927-nm Fractionated Thulium Laser Energy and Polydeoxyribonucleotide Injections
A treatment combining laser energy and injections improved hair loss and unexpectedly also reduced hair graying.
research Role of Dermoscopy in the Diagnosis of Alopecia
Dermoscopy is useful for diagnosing different types of hair loss.
research Immunomorphological Features of Female Patient’s Skin with Androgenetic Alopecia in the Treatment of Platelet-Rich Plasma in Combination with Topical Minoxidil 2% Lotion
The combined treatment improved scalp health in women with early-stage hair loss.
research Dermoscopic Features of Androgenetic Alopecia and Their Clinical Implications
Hair diameter difference, brown skin discoloration around hair follicles, and missing hair in certain areas are key signs of androgenetic alopecia (commonly known as hair loss) when viewed under a dermoscope.
research New Pattern Hair Loss in Young Turkish Women: What's Wrong in Their Daily Life?
Frequent use of hair straighteners can cause hair loss similar to scarring alopecia in young Turkish women.
research A Novel Link Between Human Hair Follicle Neuroimmunology and Mitochondrial Biology: Substance P Increases Intrafollicular Oxidative Stress and Mitochondrial Biogenesis
Substance P may contribute to hair loss by increasing oxidative stress and mitochondrial activity in hair follicles.
research Keratosis Pilaris With Adjacent Haemosiderin Deposition: A Clue to Scurvy
A man's skin condition and poor diet led to a scurvy diagnosis.
research A Case of Scarring Alopecia
The woman was diagnosed with lichen planopilaris and can be treated with corticosteroids.
research Trichoscopy Update 2011
Trichoscopy is a useful tool for diagnosing different hair and scalp diseases by their unique visual features.
research Induction of Ornithine Decarboxylase in Specific Subpopulations of Murine Epidermal Cells Following Multiple Exposures to 12-O-Tetradecanoylphorbol-13-Acetate, Mezerein, and Ethyl Phenylpropriolate
The study investigated the effects of multiple exposures to 12-O-tetradecanoylphorbol-13-acetate (TPA), mezerein, and ethyl phenylpropriolate (EPP) on murine epidermal cells, focusing on the induction of ornithine decarboxylase (ODC) activity. While single applications of these agents caused similar hyperplasia and ODC induction, multiple treatments revealed significant differences in ODC activity, with TPA and mezerein inducing more than EPP. Immunocytochemical analysis showed distinct patterns of ODC-positive cells, with TPA prominently affecting perifollicular cells, mezerein affecting both interfollicular and perifollicular areas, and EPP affecting only interfollicular cells. Flow cytometry identified three keratinocyte subpopulations, with TPA causing the expansion of an intermediate-sized subpopulation not seen with EPP or mezerein. The findings suggested that TPA, a potent tumor promoter, selectively expanded a keratinocyte subpopulation hyperinducible for ODC, potentially important for neoplastic transformation, while mezerein and EPP were less effective in this regard.
research Alopecia Areata in a Rhesus Monkey (Macaca Mulatta)
The monkey's hair loss was due to an autoimmune disease, not genetics.
research Short-Term Biomarkers of Cigarette Smoke Condensate Tumor Promoting Potential in Mouse Skin
The study investigated the effects of cigarette smoke condensates (CSCs) on mouse skin, focusing on hyperplasia and inflammation as short-term biomarkers of tumor promotion. Using a truncated initiation-promotion protocol, the research assessed epidermal thickness, proliferative index, and ornithine decarboxylase (ODC) expression after CSC application. Results showed that CSCs increased these markers, with partial reversibility in interfollicular areas but sustained elevation in perifollicular regions. The study highlighted perifollicular ODC expression as a promising indicator for evaluating CSCs due to its rapid induction, low threshold, and potential to reflect irreversible changes, aligning with the notion that ODC expression is crucial for tumor promotion and that tumors primarily originate in the perifollicular epidermis.
research Nevus Comedonicus of the Scalp
A 10-year-old boy was diagnosed with a rare scalp condition causing hair loss and treated with a topical cream.
research Environmental Pathobiology of Frontal Fibrosing Alopecia: A Link Between Linalool Sensitization and FFA Development
Being allergic to linalool, a common fragrance ingredient, might contribute to developing frontal fibrosing alopecia.
research Dandruff Is Associated With Perturbations of Hair Follicle Immune Privilege and the Infundibular and Epidermal Immune Microenvironment
Dandruff is linked to changes in the immune system of hair follicles and skin.
research IL-15 Prolongs Hair Growth and Acts as a Guardian of Human Hair Follicle Immune Privilege
IL-15 helps maintain hair growth and protects the immune status of hair follicles.
research Clinical Pathological Observations and Animal Experimental Study of Trichotillomania Patients
Trichotillomania is more common in young females and often linked to stress and psychiatric conditions, with hair loss and increased catagen hair observed.
research The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation
AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.
research Latest Understanding and Treatment of Alopecia Areata
New treatments for alopecia areata, like JAK inhibitors and immunomodulators, are promising.
research Calcitonin Gene-Related Peptide (CGRP) May Award Relative Protection from Interferon-γ-Induced Collapse of Human Hair Follicle Immune Privilege
CGRP may help protect hair follicles from immune system attacks, potentially slowing hair loss.
research Eosinophilic Pustular Folliculitis Involving Labial Mucosa, Which Improved with Naproxen
Naproxen effectively treated a girl's eosinophilic pustular folliculitis when other treatments failed.
research Patterned Hair Loss: A 47-Year-Old Man With Symmetrical Hair Loss and Itching Diagnosed With Fibrosing Alopecia in a Pattern Distribution
A 47-year-old man was diagnosed with a specific type of hair loss and advised to use certain medications and avoid hair transplants.
research New England Dermatological Society: A 37-Year-Old Woman with Pruritic Erythematous Lesion Leading to Scarring Alopecia
The woman's widespread skin condition did not improve despite various treatments.