Immunomorphological Features of Female Patient’s Skin with Androgenetic Alopecia in the Treatment of Platelet-Rich Plasma in Combination with Topical Minoxidil 2% Lotion

October 2021 in “ Technology transfer: innovative solutions in medicine ”

Olena Salyenkova

androgenetic alopecia platelet-rich plasma minoxidil inflammatory perifollicular infiltration growth polypeptide imbalances oxidative stress enzyme accumulation collagen IV accumulation AGA PRP Rogaine

TLDR The combined treatment improved scalp health in women with early-stage hair loss.

The study examined the immunohistochemical changes in scalp biopsies of 30 female patients with early-stage androgenetic alopecia (AGA) before and after a 3-month treatment combining platelet-rich plasma (PRP) injections and topical minoxidil 2% lotion. Results showed that AGA is associated with inflammatory perifollicular infiltration, growth polypeptide imbalances, oxidative stress enzyme accumulation, and pathological collagen IV accumulation. The combined treatment normalized these immunohistochemical parameters, suggesting its potential for long-term therapeutic effects. However, further research is needed to better understand AGA pathomorphology and standardize PRP treatment techniques.

View this study on journal.eu-jr.eu →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 15 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs

in Research/Science 3 upvotes 1 year ago

The review discusses traditional hair loss treatments like minoxidil and finasteride, and newer options like Low-Level Laser Therapy, microneedling, and platelet-rich plasma for androgenetic alopecia. It highlights the need for more high-quality trials to assess these treatments' effectiveness and standardized protocols for emerging therapies.

community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

in Treatment 89 upvotes 4 years ago

Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.

community SCUBE3 and GT20029 could be the closet thing to a cure: Hair Follicle Regeneration and Protection Against DHT

in Research/Science 15 upvotes 1 year ago

SCUBE3 and GT20029 are potential treatments for hair loss, with SCUBE3 stimulating hair growth and GT20029 protecting against DHT. A combined approach using SCUBE3, finasteride or dutasteride, and later GT20029 could provide a comprehensive treatment for androgenetic alopecia.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 41 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Reddit’s amatorial meta analysis of 17 already avaliable hair loss prevention treatments that were found to be effective in clinical studies but are not FDA approved for MPB. PROS and CONS. (2022 Guide if Finasteride and Minoxidil are not working/ give you sides/are not enough) 77 studies linked!

in Research/Science 586 upvotes 2 years ago

The post and conversation are about hair loss treatments that have been found to be effective in studies. There are 19 different treatments mentioned, including oral minoxidil, oral dutasteride, topical finasteride, RU58841, and more. The best treatment for an individual depends on factors like availability, cost, side effects, and personal preferences.

Related Research

4 / 4 results

research Immunomorphological Features of Female Patient’s Skin with Androgenetic Alopecia in the Treatment of Platelet-Rich Plasma in Combination with Topical Minoxidil 2% Lotion

October 2021 in “Technology transfer: innovative solutions in medicine”

The combined treatment improved scalp health in women with early-stage hair loss.

Oral Minoxidil Improves Background Hair Thickness in Lichen Planopilaris