Clinical Pathological Observations and Animal Experimental Study of Trichotillomania Patients

    January 1999 in “ 대한피부과학회지
    정태안, 권경술, 장호선, 오창근, 조시형
    TLDR Trichotillomania is more common in young females and often linked to stress and psychiatric conditions, with hair loss and increased catagen hair observed.
    In a retrospective study conducted from 1988 to 1997 at the Department of Dermatology in Pusan National University Hospital, 20 cases of trichotillomania were examined. Trichotillomania, a condition where patients repeatedly manipulate their hair leading to incomplete alopecia, was found to be more common in females (60%) and individuals between 7 and 18 years old (75%). The most common initial site of hair loss was the parietal region (55%). Some patients reported pruritus (25%), chronic headache (10%), and had habits like onychophagia (20%), trichophagia (5%), and thumb sucking (5%). Many patients (70%) denied a history of hair-plucking. Psychiatric consultation revealed conditions like obsessive disorder (33%), social phobia (17%), and dysmorphic disorder (8%). The most common triggering factor was school-related mental stress (25%). Histopathological examination showed empty hair follicles without perifollicular infiltration (100%) and increased catagen hair (90%). An experiment on rabbits showed similar findings after hair plucking, with all hair follicles changing into catagen and telogen stage simultaneously and new hair growth observed.
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