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The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

Healthcare providers need better education and policies to serve transgender individuals effectively.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Measuring the distance from the anus to the clitoris may moderately help diagnose polycystic ovary syndrome, especially in certain cases.

α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

Pediatric dermatologists need to understand the unique skin health needs of LGBTQIA youth to provide better care.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Some skin diseases and their treatments can negatively affect male fertility.

Negative expectations can cause adverse effects in dermatology treatments, like with finasteride for baldness, and careful communication can help reduce these nocebo responses.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.

The critique suggests that Wilton's work unintentionally supports the very stereotypes it aims to question and calls for a broader, more inclusive approach to understanding gender.

Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.

Testosterone is crucial for development, growth, and various body functions in mammals.

Old drugs can be used for new treatments, saving time and money, but there are challenges like needing more evidence and legal concerns.

Platelet-rich plasma mesotherapy improved symptoms in patients with corticosteroid-induced rosacea-like dermatitis.

Skin doctors should know about skin and kidney disease links to prevent serious kidney problems.

The conclusion of the case is not provided in the summary.

Non-infectious skin conditions are more common than infectious ones in Kashmir, but community areas see more infections, suggesting a need for better skin care services in primary health care.

A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.

Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.

Hormones significantly affect women's sexual function, and more research is needed to improve treatments for sexual dysfunction with minimal side effects.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Tadalafil is effective for treating urinary symptoms in men with BPH.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

Dihydrotestosterone gel before hypospadias surgery led to less scarring but raised concerns about potential psychological effects and skin changes.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.