This review discusses the potential effectiveness and regenerative promise of Platelet-Rich Plasma in treating cicatricial alopecia, while emphasizing the need for standardized research methods and further studies.
5 citations
,
September 2023 in “Clinical Endocrinology” This study suggests revising PCOS diagnostic criteria to integrate the polymenorrhoea subcategory due to shared metabolic dysfunctions with oligomenorrhoea.
9 citations
,
February 2007 in “JAMA” PCOS is a common inherited condition causing cysts, irregular periods, and increased diabetes risk in women.
In this study of Andean Ecuadorian women with PCOS, phenotypes A and B were more prevalent and associated with higher risks of insulin resistance, anovulation, and metabolic disorders compared to phenotypes C and D.
January 2026 in “Dermatologic Therapy” This study suggests that autologous platelet concentrates may improve inflammatory activity, disease control, and hair regrowth in primary cicatricial alopecia, but the evidence is limited by small sample sizes and study quality.
January 2022 in “International journal of zoological investigations” In this study, the prevalence of PCOS was reported to be approximately 10% among urban college girls in Chennai, with increased testosterone and decreased progesterone levels observed.
6 citations
,
August 2022 in “Dermatologic therapy” This study reports that platelet-rich plasma therapy resulted in temporary hair growth in patients with stabilized Central Centrifugal Cicatricial Alopecia.
9 citations
,
July 2007 in “Circulation Research” This study found that disruptions in planar cell polarity signaling are implicated in congenital heart defects and cardiomyopathy in developing mouse hearts, associated with early cardiomyocyte disorganization and improper heart looping.
30 citations
,
September 2013 in “PubMed” This study found that Chinese women with PCOS have a high prevalence of mild to moderate NAFLD, particularly when BMI is ≥24 kg/m(2), emphasizing the role of insulin resistance and metabolic abnormalities.
January 2024 in “Biomarker Insights” This study found significant associations between PCOS susceptibility and specific genetic variants in the APOA5 and PLIN1 genes among Western Saudi women, identifying novel alleles and genotypes that may influence PCOS risk and related clinical characteristics.
3 citations
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July 2015 in “International Journal of School Health” This study found that in a sample of female adolescents in Shiraz, the most common PCOS phenotype was hyperandrogenic with polycystic ovary syndrome, warranting further investigation due to associated risks.
1 citations
,
July 2025 in “Middle East Fertility Society Journal” This study found that women with PCOS had significantly higher levels of several autoantibodies compared to healthy controls, suggesting a potential autoimmune component to PCOS that might aid in better disease characterization and personalized management.
1 citations
,
May 2020 in “Journal of The American Academy of Dermatology” This study found that women with hair thinning presenting to a specialty clinic often had PCOS, with irregular menses and clinical signs like hirsutism and acanthosis nigricans being key indicators.
April 2018 in “Journal of Investigative Dermatology” This study found that palmoplantar pustulosis patients exhibited oral dysbiosis, particularly among those with pustulotic arthro-osteosis, as compared to healthy controls.
41 citations
,
June 2022 in “Biomedicines” This study proposes reclassifying PCOS into two distinct phenotypes based on androgen levels and suggests androgen supplementation may overcome IVF resistance in one group with advancing age.
April 2026 in “ScholarWorks (Walden University)” This phenomenological study reported that Malaysian women with PCOS experience significant emotional, social, and physical challenges affecting their quality of life, highlighting the need for improved patient-centered care.
November 2017 in “Elsevier eBooks” This article reviews the complications and health risks associated with polycystic ovary syndrome and reports no new clinical findings.
January 2026 in “Scholars Journal of Medical Case Reports” This article outlines a diagnostic and treatment approach for polycystic ovarian syndrome in young women, emphasizing lifestyle modifications, hormonal treatments, and specialist referrals for managing symptoms and fertility concerns.
2 citations
,
April 2021 in “Reproductive health of woman” This study found that among women with PCOS, the most common clinical symptoms were menstrual dysfunction, infertility, acne, and hirsutism, with the non-androgenic phenotype being the most frequently identified.
April 2023 in “Cancer research” This study suggests that KRTAP2-3 may serve as a novel biomarker to identify cells in the polyaneuploid cancer cell state, which is linked to therapy resistance and poor prognosis in prostate cancer.
March 2024 in “Journal of Rawalpindi Medical College/Journal Rawalpindi Medical College” This study observed that skin conditions like hirsutism, acne, and androgenic alopecia were common in PCOS patients and may aid in its diagnosis.
April 2022 in “International Journal of Science and Research (IJSR)” This study found a correlation between polycystic ovarian disease and infertility among women, with 72% of participants experiencing difficulty conceiving.
3 citations
,
September 2010 in “Acta Médica Portuguesa” This review explores the psychosocial impact of PCOS symptoms on health-related quality of life, emphasizing the need for multidisciplinary care and individual perspectives, but reports no new research findings.
1 citations
,
November 2023 This study examined the prevalence and management of PCOD, finding that it primarily affects unmarried women aged 18-25, causing symptoms like irregular periods and infertility, with many opting for medication and lifestyle changes despite mixed beliefs about their effectiveness.
2 citations
,
February 2018 in “InTech eBooks” This book discusses current research on polycystic ovary syndrome, including diagnosis, management, and the impact of lifestyle changes, without reporting new clinical results.
December 2021 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Men can have genetic risks for PCOS-related traits like obesity and diabetes.
February 2020 in “Research Square (Research Square)” This study reported that health-related quality of life was significantly lower in adult Mediterranean women with PCOS and the anovulatory phenotype compared to controls at a tertiary hospital.
January 2025 in “Directory of Open access Books (OAPEN Foundation)” This book reviews the symptoms, diagnosis, and treatments for Polycystic Ovary Syndrome, providing a comprehensive exploration but reports no new clinical results.
1 citations
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February 2024 in “Gynecological Endocrinology” This study found that cyclic MPA is as effective as OCPs in resuming ovulation among women with PCOS, offering a viable alternative for those who cannot or choose not to use OCPs.
3 citations
,
February 2018 in “Experimental and Molecular Medicine/Experimental and molecular medicine” This study suggests that hair loss disorders like Marie Unna hereditary hypotrichosis may result from mutations that disrupt post-transcriptional regulation of HR protein expression by PCPB2 interacting with Hr mRNA.