Phenotypic Characterization of Patients with Polycystic Ovary Syndrome in a Population from the Ecuadorian Andes: A Cross-Sectional Study

    December 2023
    María Elena Espinosa, Raúl Sánchez, Támara Otzen, Estefanía Bautista-Valarezo, Stephanie Aguiar, Isabel Corrales Gutiérrez, Fátima León-Larios, Carlos Manterola
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    TLDR PCOS phenotypes A and B are more common and linked to higher health risks in women from the Ecuadorian Andes.
    This cross-sectional study characterizes the phenotypic variations of Polycystic Ovary Syndrome (PCOS) in 92 women from the Ecuadorian Andes. The study found that phenotypes A and B, which are more common, are strongly associated with oligo-amenorrhea, acne, higher triglyceride levels, and BMI, indicating higher risks of insulin resistance and metabolic disorders. In contrast, phenotypes C and D are more associated with alopecia. The study highlights the influence of ethnic diversity and sociocultural habits on the prevalence and clinical manifestations of PCOS phenotypes in this population.
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