Characteristics of Phenotypes (Clinical Variants) of Polycystic Ovary Syndrome in Women of Reproductive Age

    April 2021 in “ Reproductive health of woman ”
    V.G. Syusyuka, М.Ю. Сергієнко, H. I. Makurina, О.А. Єршова, А.С. Чорненька
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    TLDR Most women with polycystic ovary syndrome (PCOS) have menstrual issues, infertility, acne, and excessive body hair, with the most common type being the non-androgenic phenotype.
    The study involved 34 women with polycystic ovary syndrome (PCOS) and 30 healthy women. It was found that 73.5% of the women with PCOS had menstrual cycle disorders, 52.9% had infertility, and 47.1% had acne, while 41.2% had hirsutism. Hyperandrogenism was present in 55.9% of the women with PCOS, indicated by higher levels of androstenedione and free testosterone. The most common clinical variant of PCOS was the non-androgenic phenotype (phenotype D), found in 44.1% of the women. The classic (phenotype A) and incomplete classic (phenotype B) were found in 32.4% and 14.7% of women respectively, and only 8.8% had the ovulatory phenotype (phenotype C).
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