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This study found that sebaceous glands in the skin are primarily renewed by their own stem cells during normal conditions, but after injury, they regenerate through stem cells from hair follicles, highlighting stem cell plasticity and regeneration capabilities.

This review highlights the promising role of stem cell therapy in treating resistant diseases, while also addressing the challenges in production and clinical application, emphasizing the need for standardized manufacturing and quality assurance to enhance efficacy and safety in clinical translational research.

In this study, the researchers observed that inducing and then withdrawing β-catenin expression in a bigenic mouse model caused reversible changes in skin morphology, indicating dependence on β-catenin signaling.

This review discusses the role of metabolism in maintaining adult stem cell homeostasis with aging and highlights the potential benefits of dietary restrictions on stem cell function and longevity. It reports no new clinical results and emphasizes the need for further molecular studies.

This review examines the current applications and potential of artificial intelligence in healthcare, highlighting its role in improving prevention, diagnosis, and treatment across multiple major disease areas, but reports no new experimental findings.

This essay explores Harriet E. Wilson's spiritualist career in Boston but reports no new findings; it provides context to her autobiographical novel "Our Nig" and early struggles.

In this study, researchers used patient-derived organoids to model metastasis in colorectal cancer and discovered that cancer cells temporarily switch to a wound-healing program, orchestrated by reduced EZH2 activity and YAP signaling, before spreading to new organs.

This review discusses the role of epithelial–mesenchymal transition in cutaneous fibrotic disorders and highlights potential molecular targets for therapy, but reports no new clinical results.

This study explores the complex mechanisms of skin aging, including cellular senescence and disrupted communication, and highlights rejuvenation strategies like gene expression rewiring and microbiome modulation, offering potential frameworks for regenerative therapies and precise interventions in skin and systemic aging.

The researchers observed that in cichlid fishes with different dental structures, tooth replacement accelerated more than three times following tooth extraction, alongside distinct changes in gene expression and cellular interactions over one week, providing insights into tooth regeneration mechanisms in vertebrates.

This study found that exosomes derived from human amniotic mesenchymal stem cells enhanced stem cell proliferation and structural restoration in irradiated salivary glands of rats, with significant improvements observed by day 7, suggesting activation of the Wnt signaling pathway.

In this study, original natural organic cosmetics with a natural index of ≥ 90% and efficacy patents increased purchase intention and reduced promotional dependency in the US market.

This literature review discusses the challenges and potential strategies for creating fully functional hair follicles capable of active cycling, emphasizing the molecular mechanisms, signaling pathways, and innovative regenerative techniques, such as hair micropatterning and three-dimensional printing, crucial for optimizing hair follicle regeneration.

This study revealed that during avian skin development, complex tissue architecture results from specific cellular flows and mechanical processes that guide feather bud protrusion and elongation, with distinct differences noted in scale development, where rigidity restricts such transformations.

This study synthesizes knowledge of how dendritic cell signals, epithelial integrins, and fibroblast activity converge on TGF-β1 to maintain or disrupt skin healing, contrasting normal and fibrotic scar formation and suggesting possible integrin and immune-targeted treatments for skin fibrosis.

This abstract serves as a promotional notice for a book titled "Essentials of Food Science and Nutrition" by several authors, offering it for sale at a low price, but does not report any research results.

This review discusses the insights gained from single-cell RNA sequencing of fibroblasts in various cancers and wound healing, highlighting differences in gene expression and novel interactions.

In this review, the authors explore strategies for inducing scarless skin regeneration by modulating dermal signaling or specific fibroblast subsets to promote the formation of new hair follicles in wounds, particularly focusing on mimicking neonatal skin's regenerative capabilities.

This study used a novel fluorescent tagging method in mice to observe collagen IV dynamics during hair follicle development, revealing that alterations in basement membrane turnover can influence epithelial progenitor cell behavior and organ morphology by affecting cell proliferation and movement.

This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.

In this study, peptide-based nanoparticles were successfully used to deliver the CRISPR-Cas9 system into cancer cells, effectively targeting and editing KRAS mutations, suggesting promising therapeutic potential for cancer treatment.

In this study, researchers observed that after mesenchymal cell division in mouse and chicken embryonic skin, elevated migration speed and persistence for 180 minutes contribute to mesenchymal dispersal and preferential recruitment to dermal condensates.

This review discusses the interplay between signaling/transcription factor-mediated and epigenetic mechanisms in skin development and regeneration, highlighting the need for further exploration of epigenome reorganization in these processes.

Activating the Eda/Edar pathway improves wound healing by enhancing hair follicle growth.

This chapter reviews the skin's structure and its clinical relevance, highlighting connective tissue diseases and the potential for novel treatments like protein, cell, or stem cell transfer, but reports no new findings.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

This study found that normal murine hair follicles are direct targets for melatonin bioregulation, expressing receptors that are regulated in a hair cycle-dependent manner, influencing keratinocyte apoptosis.

This dissertation reported that the loss of Ovol2 impairs hair follicle regeneration and wound repair in mice, highlighting its role in regulating directional migration of epithelial cells.

This review discusses the current understanding of polycystic ovary syndrome, focusing on its epidemiology, pathophysiology, diagnosis, management, and future research directions, but reports no new clinical results.

This review summarizes fundamental concepts and recent advancements in hair follicle biology, including insights from mouse models into broader molecular and cellular processes relevant to regeneration and development.