Novel Tissue Mechanics-Guided Cellular Flows Enable the Evolution of Feather Follicles
October 2025
Research cited in this study
8 / 8 resultsresearch Evo Devo of the Vertebrate Integument
The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
research Progenitor-Derived Endothelin Controls Dermal Sheath Contraction for Hair Follicle Regression
A specific signal from hair cells controls the tightening of the surrounding muscle, which is necessary for hair shedding.
research Symmetry Breaking of Tissue Mechanics in Wound-Induced Hair Follicle Regeneration of Laboratory and Spiny Mice
Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.
research Hair Follicle Stem Cells as a Skin-Organizing Signaling Center During Adult Homeostasis
Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
research Comprehensive Molecular and Cellular Studies Suggest Avian Scutate Scales Are Secondarily Derived from Feathers, and More Distant from Reptilian Scales
Bird scales evolved from feathers, not reptile scales.
research Transcriptome Analyses of Reprogrammed Feather/Scale Chimeric Explants Revealed Co-Expressed Epithelial Gene Networks During Organ Specification
Key genes can rewire networks, changing skin appendage types.
research Development, Regeneration, and Evolution of Feathers
Feathers are crucial for understanding bird evolution, development, and have inspired biomimetic research.
research Sprouty/FGF Signaling Regulates Proximal–Distal Feather Morphology and Dermal Papillae Size
Sprouty and FGF balance is crucial for normal feather shape and size.