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    Did you mean Epithelial Sac?
    Glossary Epithelial Sac

    small, enclosed structure of epithelial cells around hair follicle

    An epithelial sac is a small, enclosed structure composed of epithelial cells, which are cells that line the surfaces and cavities of the body. In the context of hair biology, an epithelial sac can refer to the structure that surrounds the developing hair follicle, playing a crucial role in the formation and growth of hair. This sac provides a protective environment and supplies necessary nutrients to the growing hair shaft.

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    1. Treatment of Acne Scar Contraction Using Autologous Cultured Epithelial Sheet Transplantation: A Report of Four Cases Cureus · 2025
    2. Nestin as a marker of unipotent epithelial progenitor cell differentiation into outer root sheath keratinocytes in embryonic and adult hair follicles Research Square (Research Square) · 2022
    3. Epithelial–mesenchymal transition in keloid tissues and TGF‐β1–induced hair follicle outer root sheath keratinocytes Wound repair and regeneration · 2015 · 46 citations
    4. K6irs1, K6irs2, K6irs3, and K6irs4 Represent the Inner-Root-Sheath-Specific Type II Epithelial Keratins of the Human Hair Follicle1 Journal of Investigative Dermatology · 2003 · 130 citations
    5. A Novel Epithelial Keratin, hK6irs1, is Expressed Differentially in All Layers of the Inner Root Sheath, Including Specialized Huxley Cells (Flügelzellen) of the Human Hair Follicle Journal of Investigative Dermatology · 2002 · 86 citations
    6. VEGF165 modulates proliferation, adhesion, migration and differentiation of cultured human outer root sheath cells from central hair follicle epithelium through VEGFR-2 activation in vitro Journal of Dermatological Science · 2013 · 35 citations
    7. Hair follicle-derived epithelial sheet has potential in vitiligo treatment medRxiv · 2026
    8. Nestin as a marker of unipotent epithelial progenitor cells differentiate into outer root sheath keratinocytes in embryonic and adult hair follicles Research Square (Research Square) · 2022
    9. Commentary on Clinical Application of Cultured Stratified Epithelial Sheets Grown Under Feeder or Feeder-Free Conditions for Stable Vitiligo Dermatologic Surgery · 2019
    10. Hair-follicle dermal papilla and sheath fibroblasts provide a supportive microenvironment for human skin regeneration 2017 · 3 citations
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    1. Adipocyte lipolysis activates epithelial stem cells for hair regeneration through fatty acid metabolic signaling Reddit · 26 Oct 2025