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    Cellular Basis of Accelerated Whole-Tooth Regeneration

    April 2026 in “ eLife
    Talha Mubeen, H. He, George W. Gruenhagen … J. Todd Streelman
    Studysummary The researchers observed that in cichlid fishes with different dental structures, tooth replacement accelerated more than three times following tooth extraction, alongside distinct changes in gene expression and cellular interactions over one week, providing insights into tooth regeneration mechanisms in vertebrates.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 6

    1. Hallmarks of Regeneration Cell stem cell · 2024
    2. Parallels in Signaling Between Development and Regeneration in Ectodermal Organs Current topics in developmental biology/Current Topics in Developmental Biology · 2022
    3. Distinct Tooth Regeneration Systems Deploy a Conserved Battery of Genes EvoDevo · 2021
    4. Dental Cell Type Atlas Reveals Stem and Differentiated Cell Types in Mouse and Human Teeth Nature Communications · 2020
    5. Immune Modulation of Hair Follicle Regeneration npj Regenerative Medicine · 2020
    6. Organ-Level Quorum Sensing Directs Regeneration in Hair Stem Cell Populations Cell · 2015