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Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Flutamide effectively treats female pattern hair loss with low doses showing good liver tolerance.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.

The conclusion is that a new biopsy technique and humidity chamber help study skin mites better and suggest mite overpopulation may cause skin diseases.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.

The review suggests that understanding and treating the psychological aspect of skin disorders is important and calls for more collaboration in this field.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

FA2H is essential for normal fur and sebum production in mice.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Permanent hair dye damages hair but it mostly recovers after 8 weeks; using certain hair care products can help repair it.

Antimicrobial lotion reduces inflammation and increases hair density in hair loss patients.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.

Minoxidil lowers blood pressure, increases heart rate, and improves blood flow in dogs.

The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.

Facial plastic surgery has evolved to focus on less invasive techniques and innovative technologies for cosmetic and reconstructive procedures.

A disease causing skin issues in young adult German short-haired pointers is hereditary, with most affected dogs not responding to treatment.

Leflunomide and methotrexate are equally effective for rheumatoid arthritis but have different side effects.

The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.

More pediatric-specific research and guidelines are needed to improve hidradenitis suppurativa treatment in children and adolescents.

Prolactin may affect hair growth differently based on gender and scalp area.

Cyclosporin effectively and safely treated skin diseases in three pets with no side effects.

Combining cyclosporine A and ketoconazole can effectively treat anal furunculosis in dogs, with some experiencing recurrences and mild side effects.

Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Women with PCOS tend to have higher anxiety and depression levels compared to healthy women.