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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Women experience various skin issues at different life stages, requiring careful treatment and awareness.

Accurate diagnosis of cicatricial alopecias requires thorough scalp examination and multiple biopsy techniques.

Certain micronutrients may improve hair and nail health, but more research is needed to confirm their benefits.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Prunus mira kernels contain components that can promote hair growth in mice.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Elaine Fuchs' research shows how skin stem cells maintain health, aid in healing, and are involved in cancer.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.

The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.

Exosomes from fat-derived stem cells can potentially improve hair growth and could be a new treatment for immune-related hair loss.

The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.

CRABP2 helps increase the growth of cells important for hair growth by activating a specific growth pathway.

CRABP1 boosts hair cell growth in Hu sheep by affecting key genes.

Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.

Human dental pulp stem cell-conditioned medium, especially from hypoxic conditions, may help treat chemotherapy-induced hair loss and does not increase cancer risk.

Skin organoids from stem cells could better mimic real skin but face challenges.

Blackcurrant extract may help reduce hair loss by promoting stem cell activity in hair follicles.

Human stem cells can help form hair follicles in mice.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Sunlight exposure damages hair follicles, but certain stem cell-derived particles can reduce this damage and help with hair regeneration.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.