7 citations
,
October 1992 in “PubMed” This study investigated peptidergic nerve fibers in sinus hair follicles of various mammals and found that CGRP fibers were more densely distributed than SP fibers across different regions of the follicles.
104 citations
,
May 2003 in “Endocrinology” This study found that the vitamin D receptor in lampreys, which lack bones and hair, binds 1,25-dihydroxyvitamin D3 and may function to induce enzymes for detoxifying substances.
9 citations
,
November 2015 in “JAMA dermatology” This case study describes an elderly woman with distinctive black hair patches and scalp pigmentation, but it does not provide a diagnosis or new findings.
19 citations
,
May 1992 in “International Journal of Dermatology” This article discusses less commonly used and experimental treatments for vitiligo, focusing on therapies other than psoralen, but does not report new clinical results.
43 citations
,
September 2017 in “Lasers in Surgery and Medicine” This study found that LED light irradiation induced proliferation and migration of human outer root sheath cells, potentially through the stimulation of the Wnt/β-catenin and ERK signaling pathways.
1 citations
,
March 2018 in “BMJ case reports” This case report describes a 30-year-old bisexual African man with neurological symptoms, generalized wasting, and ophthalmological findings, but reports no new clinical research results.
December 2025 in “International Journal of Molecular Sciences” This study found that an aqueous extract of Bacopa procumbens improved motor function and preserved neuronal structure in a mouse model of Parkinson's disease, suggesting its neuroprotective potential.
3 citations
,
December 1975 in “PubMed” This study found that acid and alkaline phosphatases serve different functions in Beagle dog skin, with ALP primarily involved in growth processes and ACP in phospholipid breakdown.
57 citations
,
February 1994 in “Experimental dermatology” This study found that murine skin is a target for melatonin bioregulation, as melatonin affected DNA synthesis and tyrosinase activity in skin organ culture.
6 citations
,
September 2010 in “Pigment Cell & Melanoma Research” This article discusses the roles of different proteins in melanogenesis and proposes a hypothesis to explain the diversity of human hair pigmentation, but it reports no new experimental results.
9 citations
,
June 1959 in “Archives of dermatology” This article discusses the importance of integrating clinical observations with laboratory research, emphasizing the need for clinicians to collaborate with researchers to address medical problems.
January 2024 in “Biological & pharmaceutical bulletin” In this study, Panax ginseng extract and its ginsenosides were found to stimulate the proliferation of hair-related cells and promote the transition from the telogen to the anagen phase, enhancing hair-shaft growth by suppressing BMP4 expression in human dermal papilla cells.
4 citations
,
January 1982 in “Neuroendocrinology” This study found that pimozide, d-butaclamol, and pituitary pars intermedia grafts darken hair color in agouti C3H Avy mice, suggesting dopaminergic inhibition influences peptide-controlled hair color cycling.
58 citations
,
February 2016 in “Scientific reports” This study found that dual inhibition of BACE1 and BACE2 in mice affects melanosome maturation and causes dose-dependent hair depigmentation without altering retinal morphology.
65 citations
,
November 2004 in “Journal of the American Academy of Dermatology” This article reports a case where the IOP-lowering drug bimatoprost was associated with eyelash hypertrichosis.
November 2021 in “Natural product research” This study observed that the aqueous extract of roasted Alocasia macrorrhizos tubers led to hair follicle repigmentation and reduced epidermal thickness in a murine model of Vitiligo.
3 citations
,
February 1943 in “The American journal of digestive diseases/American journal of digestive diseases” Riboflavin helps heal bed sores, inositol aids skin diseases, and calcium pantothenate doesn't prevent gray hair.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Alopecia patients have a less active liver monoxygenase system, which can be treated with photochemotherapy and system inducers.
4 citations
,
January 1993 in “Clinical Chemistry and Laboratory Medicine (CCLM)” This study developed a highly sensitive fluorescent assay for measuring enzyme activity in single hair follicles, allowing the efficient analysis of over 100 samples per day.
July 2020 in “Nepalese journal of ophthalmology” This case report from Nepal describes a five-year-old boy with Hutchinson Gilford Progeria Syndrome experiencing ocular manifestations, highlighting the role of ocular senescence in this genetic disorder.
109 citations
,
October 2007 in “Journal of pineal research” This study suggests that melatonin plays a role in hair follicle function by modulating growth and pigmentation, and it may act as a protective agent in active hair growth phases.
July 2013 in “Journal of clinical & experimental dermatology research” This study found that prototype right heart circulatory assist devices significantly improved hemodynamics and reduced pulmonary vascular resistances in piglet models of acute hemodynamic shock.
22 citations
,
April 2012 in “The American journal of pathology” This study found that the loss of Msx2 in knockout mice led to phenotypes similar to Peters anomaly and microphthalmia, suggesting that MSX2 plays a critical role in anterior segment development of the eye.
January 2024 in “International Journal of Trichology” This study suggests that serum paroxonase 1 levels are decreased in patients with androgenetic alopecia and may serve as a useful biomarker for this condition.
5 citations
,
September 2014 in “Journal of Pharmaceutical Sciences” 16 citations
,
October 2004 in “Journal of Investigative Dermatology” This study found that normal human melanocytes can be protected from apoptosis through both PI 3-kinase/Akt-dependent and independent pathways, with insulin and TPA offering nearly complete protection.
4 citations
,
November 1981 in “Indian Journal of Dermatology Venereology and Leprology” This study observed that oral calcium pantothenate may reverse hair greying in some adolescent cases, as seen in two girls whose grey hairs turned black after treatment.
February 2025 in “Cosmetics” This narrative review explored how blue light therapy may offer therapeutic benefits for various skin disorders by affecting microbial activity and immune responses, promoting hair growth, and aiding skin rejuvenation and healing.
May 2023 in “International journal of molecular sciences” This study investigated the role of the ABCA4 gene in human keratinocytes and hair follicle stem cells and found that silencing the ABCA4 gene increases the harmful effects of all-trans-retinal on hair follicle stem cells.
11 citations
,
August 2010 in “Developmental neurobiology” This study suggests that Ptprq in the hair bundles may exist as multiple isoforms that are differentially expressed throughout development and affect the organization of stereocilia in the chick inner ear.