216 citations
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September 2020 in “Scientific African” This review discusses the potential of pumpkin seeds as a functional food ingredient, highlighting their promising bioactive compounds and health benefits, but reports no new clinical results.
36 citations
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January 2014 in “Evidence-based Complementary and Alternative Medicine” This study found that men with androgenetic alopecia treated with pumpkin seed oil for 24 weeks experienced a notable 40% increase in hair count compared to a 10% increase with a placebo.
15 citations
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May 2022 in “Fermentation” This study found that fermented camel milk containing 50% pumpkin seed milk significantly improved oxidative stress markers in rats and enhanced sensory and physicochemical properties compared to untreated groups.
15 citations
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June 2018 in “Food Reviews International” This review discusses the potential benefits of pumpkin seed oil for men's health, particularly in conditions such as benign prostatic hyperplasia, overactive bladder, and androgenic alopecia, but reports no new clinical results.
13 citations
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February 2019 in “Journal of Microencapsulation” This study focused on designing a niosome formulation that encapsulates pumpkin seed oil for topical use, achieving high entrapment efficiency and stability over three months.
12 citations
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January 2018 in “Pharmacology & pharmacy” This study found that components derived from Uromedic® pumpkin seeds, especially Δ7-sterols, may inhibit DHT production and AR binding, potentially benefiting prostate and bladder health by moderating these mechanisms.
7 citations
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July 2022 in “Pharmaceuticals” This study reports that pumpkin seed oil-loaded niosomes significantly decreased hair loss and increased hair growth indicators in vivo, suggesting potential as a natural anti-hair loss therapy.
4 citations
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January 2024 in “Scientific Reports” Pumpkin seeds may help expel parasites, but findings are retracted.
4 citations
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February 2021 in “Journal of Cosmetic Dermatology” This study found that pumpkin seed oil significantly improved hair parameters in females with pattern hair loss, demonstrating potential as a treatment comparable to minoxidil 5% foam.
3 citations
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January 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study in mice found that topical pumpkin seed oil promoted hair growth and could be a promising alternative treatment for male pattern alopecia.
3 citations
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January 2015 in “Evidence-based Complementary and Alternative Medicine” This review discusses pumpkin seed oil as a potential treatment for androgenetic alopecia but reports no clinical results on its effects on frontal hair loss; it emphasizes the need for further research.
2 citations
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October 2021 in “Egyptian Journal of Chemistry” In this study, researchers used pumpkin aqueous extract to create iron nanoparticles, finding them effective at inhibiting harmful bacteria found in burn and wound infections, as well as promoting burn healing and hair growth in a laboratory mouse model.
1 citations
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January 2024 in “Journal of Food Processing and Preservation” This study found that adding microcapsulated pumpkin seed protein hydrolysate to aloe vera drinks improved antioxidant activity, taste, and shelf life, with chitosan-alginate microcapsules effectively inhibiting microbial growth during 30 days of refrigerated storage.
1 citations
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June 2022 in “Pakistan biomedical journal” This review discusses the potential benefits of converting pumpkin seeds, often considered industrial waste, into valuable nutrition-rich materials, but reports no new experimental results.
1 citations
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April 2022 in “Acta histochemica” This study found that oral pumpkin seed oil increased hair follicle proliferation in mice without causing liver toxicity, unlike finasteride and minoxidil which showed adverse effects.
1 citations
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July 2012 in “EFSA Journal” The Panel concluded that there is no established cause and effect relationship between the specified vitamin and pumpkin seed oil combination and the maintenance of normal hair in healthy adults.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports that a newly formulated herbal hair oil may be a stable and safe option to promote hair growth and reduce hair fall without toxic chemicals.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This research formulated a herbal hair oil using ingredients like pumpkin seed, bhringraj, and amla to reduce DHT levels and stimulate hair growth, with findings suggesting that the product is stable, suitable for the scalp, and free from toxic chemicals.
February 2025 in “Clinical & Experimental Dermatology and Therapies” In this randomized trial, oral supplementation with Serenoa repens, pumpkin seed extracts, and cysteine significantly improved the clinical effectiveness of topical 5% minoxidil lotion for treating androgenic alopecia in men and women compared to minoxidil alone, with both treatments being well tolerated.
September 2024 in “Journal of the American Academy of Dermatology” No specific results were reported in this abstract; it aims to explore the psychological effects of hair loss conditions like Chronic Telogen Effluvium and Androgenetic Alopecia, emphasizing the potential link between micronutrient deficiency and hair health.
July 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This study conducted virtual simulations and ADME/T analysis on pumpkin seed compounds to evaluate their interactions with the 5-alpha-reductase enzyme, potentially supporting their use in treating androgenetic alopecia.
June 2023 in “Journal of Ayurvedic and herbal medicine” This review article highlights the potential health benefits and pharmaceutical components of pumpkin seeds, which contain proteins, antioxidants, and essential nutrients, and discusses their traditional medicinal uses and emerging applications in the food industry.
September 2022 in “International Journal of Science and Research (IJSR)” This study evaluated a pumpkin seed oil hair gel formulated with various additives and found that the F3 formulation had promising physicochemical properties and non-irritant characteristics for potential use in treating androgenetic alopecia.
May 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This article discusses the potential health benefits of pumpkin seed oil, highlighting its uses in heart wellness, skincare, bone health, hair growth, and more, but it reports no new clinical results.
May 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses the potential health benefits of pumpkin seed oil, including heart health and hair growth, but reports no new clinical results.
January 2019 in “Journal of Dermatology and Venereology” This study reports that topical pumpkin seed oil and sesame oil were both effective in treating alopecia areata, with no significant difference in effectiveness between the two after three months.
November 2014 in “Hair transplant forum international” This study found that pumpkin seed oil may promote hair growth in men with androgenetic alopecia compared to a placebo.
This study suggests that 9-Octadecenoic acid (Z)-, 2,3-dihydroxypropyl ester from African Yam bean seeds may inhibit the human 5α-reductase II enzyme, potentially helping manage BPH, although further studies are needed.
December 2025 in “JURNAL PIJAR MIPA” This study found that a natural hair tonic spray formulated from 15% water pumpkin fruit extract promoted rabbit hair growth to a degree comparable to a synthetic control.
January 2024 in “African Journal of Biomedical Research” In this study of pregnant women in Pampore, Kashmir, 90% were found to have hypothyroidism, with 75% of thyroid dysfunction cases being diagnosed during pregnancy. The study highlights the need for better nutrition and early screening to manage gestational thyroid dysfunction effectively.