June 2022 in “Zenodo (CERN European Organization for Nuclear Research)” In a case report, this study documented successful healing of a patient with alopecia totalis using the Remember/Regeneration Therapy Method, a holistic approach combining various complementary treatments, and noted the potential for consistent outcomes in managing alopecia and other autoimmune diseases.
2 citations
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June 2024 in “Regenerative Therapy” In this study, ozone treatment was shown to increase the concentration of growth factors like EGF and TGF-β in PRP in vitro, suggesting that oxygen-rich PRP injections may provide an effective method for facial rejuvenation.
December 2013 in “미용예술경영연구” This study found that scalp treatments improved hair density and reduced the number of telogen bulbs in patients with Telogen Effluvium.
25 citations
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February 2017 in “Anticancer Research/Anticancer research” This review discusses the potential of ozone therapy as an adjuvant to radio-chemotherapy for cancer patients, noting enhanced treatment effects and improved quality of life, but it presents no new research findings.
1 citations
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May 2024 in “International journal of medicine and psychology.” In this study, researchers found that using electromagnetic radiation in the EHF range enhanced the engraftment of skin flaps in rats by improving microcirculation and reducing necrosis, with greater effects observed when paired with systemic ozone therapy.
1 citations
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October 2023 in “European journal of histochemistry” This study demonstrated that treating platelet-rich plasma with ozone or procaine in vitro led to distinct changes in platelet activity, significantly enhancing the release of platelet-derived factors without damaging the platelets, indicating potential for improved regenerative therapies.
December 2025 in “Veterinary Sciences” This study suggests that ozone bagging therapy may effectively enhance the healing of chronic distal limb wounds in horses, achieving full wound closure with minimal complications.
December 2025 in “PubMed” This case study reported that a patient experienced worsening alopecia and scarring after medical ozone therapy, highlighting significant clinical risks that may outweigh potential therapeutic benefits.
January 2020 in “Acta Scientiae Veterinariae” In this case report, a combination of ozone therapy, low-level laser, and herbal medicine gel effectively improved healing in a dog with chronic bite wounds.
November 2025 in “Undersea and Hyperbaric Medicine” This case report observed that a patient experienced worsening alopecia and scarring after medical ozone therapy, with subsequent improvement following surgical intervention and systemic hyperbaric oxygenation.
In this narrative review, the authors explored various rehabilitative techniques, including injections and physical therapies, that may enhance aesthetics and psychosocial wellbeing in patients with disabilities, emphasizing a multidisciplinary approach to improve both functional and cosmetic outcomes.
September 1995 in “PubMed” This study found that ozonized autohaemotherapy improved the hair cycle in individuals with androgenetic alopecia.
70 citations
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June 2023 in “International Journal of Molecular Sciences” In this review, researchers explored how air pollutants increase oxidative stress and inflammation in human skin, affect vitamin D synthesis, and interact with the skin microbiota, also discussing AhR/Nrf2 as a potential target for treating pollution-related skin conditions.
93 citations
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February 2008 in “Atmospheric environment” In this study, researchers found that human scalp hair, particularly when unwashed, can significantly react with ozone, reducing personal ozone exposure and increasing exposure to volatile reaction products.
36 citations
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September 1999 in “Toxicologic pathology” This study suggests that hairless dogs' skin shows sensitivity to topical corticosteroids, highlighting their potential as a model for studying the efficacy and adverse effects of these treatments on skin.
82 citations
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February 1989 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that in men with benign prostatic hyperplasia, a 3-month treatment with a long-acting GnRH agonist significantly reduced intraprostatic DHT and 3α-diol levels by about 90% and testosterone by about 75%.
79 citations
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September 2018 in “Dermatologic therapy” This study found that treatment with oral tofacitinib, alone or with other therapies, was associated with clinical improvement in most patients with recalcitrant lichen planopilaris.
29 citations
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March 1983 in “Journal of The American Academy of Dermatology” This article reviews existing and emerging treatments for psoriasis, focusing on therapy modifications due to scientific advancements, but it does not report new clinical results.
26 citations
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October 2020 in “Pediatric Dermatology” This study found that oral tofacitinib led to clinically significant improvement in alopecia areata severity scores among pre-adolescents, though results varied and further evaluation in clinical trials is needed.
January 2025 in “International Journal of Advanced Biochemistry Research” In this study, dogs diagnosed with demodicosis achieved full recovery after a single dose of fluralaner, with clinical improvement supported by negative skin scraping results by day 28, and hematobiochemical parameters normalizing over the treatment period.
June 2026 in “Frontiers in Immunology” In this case report, a 57-year-old man with severe atopic dermatitis, vitiligo, and alopecia areata showed rapid and significant improvement after treatment with the JAK1 inhibitor upadacitinib, suggesting its potential as an effective monotherapy for these co-existing conditions when conventional therapies fail.
March 2026 in “Frontiers in Cell and Developmental Biology” This review synthesizes evidence that photobiomodulation may provide robust symptomatic relief for knee osteoarthritis but indicates its potential for structural regeneration remains speculative and needs further long-term validation.
1 citations
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December 2022 in “Parodontologiya” This study found that adding carboxytherapy to standard periodontal treatment significantly reduced inflammation and restored blood flow without causing adverse effects, indicating its high effectiveness as part of a comprehensive approach to treating inflammatory periodontal diseases.
February 2023 in “Military Medical Science Letters” This study concluded that both pure-PRP and leukocyte-PRP injections significantly reduced serum CD 68 levels in knee osteoarthritis patients, with pure-PRP being more effective than leukocyte-PRP.
2 citations
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December 2020 in “American Journal of Dermatological Research and Reviews” This study found that combining 308-excimer phototherapy with intramuscular triamcinolone acetonide was effective and well tolerated for treating resistant alopecia totalis, showing a 90% overall response rate in the ten patients studied, with the best results observed in younger patients.
April 2023 in “Han'gug miyong haghoeji/Journal of the Korean society of cosmetology” This study compared the effects of direct heat perms and softening heat perms on hair, analyzing damage and morphological changes to understand their impact on hair fibers and provide foundational data for future research.
3 citations
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May 2023 in “Current Molecular Medicine” This review discusses the distinction between platelet-rich plasma and stem cell-based therapies in regenerative medicine, highlighting their different roles and stressing the importance of honest representation by commercial and health entities.
17 citations
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April 2020 in “Dermatology and Therapy” In this randomized double-blind study, 160 adults with alopecia areata showed significant improvements in hair loss severity after using a bioactive peptide cosmetic product that mimics platelet-rich plasma, while the placebo group showed no significant change, underlining the treatment's potential effectiveness.
January 2026 in “International Journal of Women s Health” This study found that a nomogram prediction model based on clinical characteristics, bone metabolism, and ovarian function can effectively predict the treatment response to long-acting GnRHa in girls with idiopathic central precocious puberty.
In this study, researchers developed and tested an herbal hair serum containing natural ingredients like banana flower extract and orange oil, which was stable and pH-balanced, with preliminary user feedback suggesting improved hair texture, reduced hair fall, and increased hair density.