Anti-Inflammatory Activity of Platelet-Rich Plasma Treatment in the Inflammation Management of Knee Osteoarthritis: Experimental Study

    February 2023 in “ Military Medical Science Letters
    Haider A. Yousif, Ajil A. Alzamily, Ihsan A. Alsalman
    TLDR Platelet-rich plasma treatments reduce knee osteoarthritis inflammation, with pure PRP being more effective.
    The study investigated the anti-inflammatory effects of Pure-PRP (P-PRP) and leukocyte-PRP (L-PRP) treatments on knee osteoarthritis (KOA) by measuring serum CD 68 levels, a biomarker for inflammation. Conducted on 48 participants aged 35-75, excluding those with diabetes, autoimmune diseases, or severe KOA, the study found that both P-PRP and L-PRP significantly reduced CD 68 levels post-injection compared to pre-injection levels, indicating anti-inflammatory activity. However, P-PRP was more effective than L-PRP in reducing inflammation, although both treatments resulted in higher CD 68 levels than the control group.
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      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

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      in Treatment  6 upvotes 1 year ago
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      in Treatment  3 upvotes 3 years ago
      Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Platelet rich plasma treatment is considered expensive but cheaper than hair transplant.

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      in Treatment  1 upvotes 2 years ago
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      in Research/Science  13 upvotes 2 years ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

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