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This review article highlights recent progress and challenges in stem cell transplantation for regenerative medicine, emphasizing its potential in tissue repair for conditions like bone and cartilage injuries, neurological disorders, and blood diseases, while stressing the importance of overcoming current obstacles for future advancements.

The researchers reported that stress-induced keratins in human skin are expressed at lower levels than those in healthy skin and are co-regulated with genes involved in differentiation, inflammation, and immunity, rather than replacing keratins of normal differentiation or indicating cell proliferation.

In this study, researchers used computational modeling and virtual screening to identify two FDA-approved drugs, Tadalafil and Finasteride, that may effectively inhibit key proteins involved in melanoma progression, suggesting potential for new therapeutic strategies against aggressive melanoma.

This review summarizes the research on bioactive materials that modulate the skin microenvironment to promote wound healing and highlights the essential role of the fascial layer, without presenting new experimental results.

This study investigated the effects of pathological α-synuclein on sebaceous gland cells in Parkinson's disease, finding that α-synuclein exposure altered cellular differentiation and lipid production, suggesting a potential link between α-synuclein and lipid dysregulation in the skin of PD patients.

This review explores the potential roles of extracellular vesicles in various medical fields, emphasizing their promise but noting the need for standardization and clinical testing before widespread application.

Fgfr2b helps maintain healthy skin and prevent cancer.

This review discusses the potential of curcumin and its formulations to mitigate neuropathic and postoperative pain, highlighting positive outcomes in preclinical and clinical studies but noting the need for further clinical research.

This review discusses how various nutrients, such as flavonoids, probiotics, and omega-3 fatty acids, may support brain health by targeting stress-related pathways, potentially offering protective effects against neurodegenerative and psychiatric disorders through their roles in oxidative stress reduction and neuroinflammation regulation.

This review utilizes clinical vignettes to detail various pain syndromes associated with multiple sclerosis, including their pathophysiology and management strategies, highlighting conditions like central neuropathic pain, Lhermitte's phenomenon, and trigeminal neuralgia as they relate to different lesion types.

This study found that low-level laser therapy at 8 J/cm2 improved cosmetic surgical scar healing in canines after thoraco-lumbar hemilaminectomy compared to controls.

This article discusses the challenges and lack of progress in improving burn care outcomes for patients aged 65 and older, highlighting the urgent need for tailored treatment protocols and better understanding of their long-term care needs.

This article reviews the potential applications, benefits, and limitations of platelet-rich plasma in medical practice and reports no new clinical results, emphasizing the need for standardized preparation and treatment protocols.

This review highlights the growing use of 3D printing in healthcare, specifically its impact on plastic surgery and prosthetic devices, and stresses the need for further research to address existing knowledge gaps.

This study observed that among patients with Myhre syndrome, those with the SMAD4 gene variant p.Arg496Cys experienced fewer symptoms like hearing loss, while those with the p.Ile500Thr variant often had severe aortic hypoplasia, highlighting the diverse symptom progression and genetic factors of this rare condition.

This review discusses the challenges and research gaps in transgender health care, highlighting the need for dedicated research infrastructure and funding to develop a more comprehensive evidence base.

This review found that finasteride monotherapy for managing LUTS/BPH significantly reduced prostate volume and improved symptoms, with sexual dysfunctions reported as notable side effects compared to placebo, but emphasizes the need for more comprehensive studies.

This review discusses the pharmacology, toxicology, and clinical efficacy of flavonoids and saponins, highlighting the need for more data on their pharmacokinetics, interactions, and toxicities as most research is still in vitro.

This article discusses key surgical techniques for optimal graft growth in hair transplantation and presents no new research findings.

This review explores the potential of extracellular vesicle therapy as a novel strategy to delay intervertebral disc degeneration and enhance tissue repair, by modulating key pathogenic mechanisms, with a focus on the molecular components and bioengineering modifications of extracellular vesicles.

This scoping review evaluates the connection between hypoxia and declining sex hormonal signaling in middle-aged individuals, proposing a "middle-aging hypovascularity hypoxia hypothesis" as a potential mechanism influencing age-related diseases, with implications for developing strategies to maintain healthspan.

This study found that Sudanese breast cancer survivors receiving hormonal or HER2-targeted therapies had better quality of life compared to those on conventional therapy.

This review explores molecular targets for head and neck squamous cell carcinoma and discusses potential advancements in radiopharmaceuticals for targeted radionuclide therapy, reporting no new clinical results.

In this study, male rats with spinal cord injury that received either E2 or DHT supplementation both showed restored expression of respiratory neuroplasticity following acute intermittent hypoxia, with E2 also enhancing overall breathing recovery.

In this study, IPL treatment for six months significantly reduced hair growth in females with faun tail nevus linked to spinal abnormalities.

This review explores the potential of multifunctional bioscaffolds in skin tissue engineering, highlighting their successful biological performance in vitro and in vivo animal models, while also identifying the demand for technological advancements to improve wound healing applications in clinical settings.

This narrative review highlights the potential of naturally occurring compounds to target specific molecular pathways and overcome resistance in advanced and recurrent papillary thyroid cancer, offering new therapeutic possibilities beyond traditional treatments like surgery and lifelong hormone replacement.

This study found that an acellular dermal matrix derived from tilapia skin significantly accelerated wound healing and improved tissue regeneration quality in mouse and pig models compared to a commercial porcine-derived matrix, suggesting its potential as a safe, cost-effective bioscaffold for skin repair.

This review discusses various diagnostic and treatment strategies for canine prostate diseases, including pharmacological options and advanced procedures, but reports no new clinical results.

In this study, researchers using visual analysis reported a rising trend in platelet-rich plasma research from 2020 to 2024, with significant contributions from the United States and China, highlighting key applications in orthopedics, tissue engineering, and potential future focuses in neurogenic pain and regenerative medicine.