Fish Acellular Dermal Matrix Promotes Repair of Full-Thickness Skin Defects in Mice and Bama Pigs

    September 2025 in “ Wound Repair and Regeneration ”
    Ziyi Wang, Zihao Lin, Ruo‐Tao Liu … Xiaojuan Wei
    Studysummary This study found that an acellular dermal matrix derived from tilapia skin significantly accelerated wound healing and improved tissue regeneration quality in mouse and pig models compared to a commercial porcine-derived matrix, suggesting its potential as a safe, cost-effective bioscaffold for skin repair.
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    Research cited in this study 6

    1. Fish Acellular Dermal Matrix Promotes Repair of Full-Thickness Skin Defects in Mice and Bama Pigs Wound Repair and Regeneration · 2025
    2. Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease Current Rheumatology Reports · 2020
    3. PI3K/Akt Signaling Pathway Is Essential for De Novo Hair Follicle Regeneration Stem Cell Research & Therapy · 2020
    4. PPAR-γ Signaling as a Key Mediator of Human Hair Follicle Physiology and Pathology Experimental Dermatology · 2019
    5. Stem Cell Dynamics, Migration, and Plasticity During Wound Healing Nature Cell Biology · 2018
    6. Skin Wound Healing in Humans and Mice: Challenges in Translational Research Journal of Dermatological Science · 2017