research Androgen Replacement in Women: A Commentary
Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.
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research The Therapeutic Use of Androgens in Women
Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
research Polycystic Ovarian Syndrome: The Androgenized Adolescent
The document concludes that PCOS in adolescents is complex and requires comprehensive care to manage its symptoms and associated health risks.
research Effectiveness and Safety of Standard Chemotherapy in Older Patients With Ovarian Cancer: A Retrospective Analysis by Age Group and Treatment Regimen
Older ovarian cancer patients live longer and tolerate weekly chemotherapy better than three-weekly treatments.
research Key Aspects of the Development of the Menstrual and Ovarian Cycle in Adolescent Girls
Late onset of first period and irregular development of sexual traits in teenage girls can lead to poorer reproductive health.
research Effect of Phlebotomy Versus Oral Contraceptives Containing Cyproterone Acetate on Clinical and Biochemical Parameters in Women with Polycystic Ovary Syndrome: A Randomized Controlled Trial
Blood removal and birth control pills both helped with hormone levels in women with PCOS, but birth control was better for regular periods and blood removal had fewer side effects.
research Association of Gly972Arg Variant of Insulin Receptor Substrate-1 and Gly1057Asp Variant of Insulin Receptor Substrate-2 with Polycystic Ovary Syndrome in the Chinese Population
The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.
research Hyperandrogenism in Polycystic Ovarian Syndrome and Role of CYP Gene Variants: A Review
Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.
research A Prospective Open Labelled Phase-II Non-Randomized Clinical Trial on Karunjchirakam Chooranam for Poly Cystic Ovarian Syndrome
Karunjchirakam Chooranam significantly improved symptoms in most PCOS cases.
research Androgens and Ovarian Function: Translation from Basic Discovery Research to Clinical Impact
Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
research The Influence of Non-Esterified Fatty Acids on Ovarian Androgen Production in IVF – Preliminary Results
High levels of fatty acids are linked to increased androgen production and inflammation in women with PCOS, which may affect IVF outcomes.
research Virilization in a Postmenopausal Woman: Ovarian Leydig Cell Tumor
A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.
research Ameliorative Effects of Rutin Against Metabolic, Biochemical, and Hormonal Disturbances in Polycystic Ovary Syndrome in Rats
Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.
research Use of Hair Products in Relation to Ovarian Cancer Risk
Certain hair straighteners and dyes may increase ovarian cancer risk, especially in African American/Black women.
research Sertoliform Endometrioid Carcinomas of the Right Ovary
A rare ovarian cancer with a good outlook was found in a woman with unusual hair growth and abdominal symptoms.
research Review on Polycystic Ovarian Syndrome (PCOS) in Case of Pregnancy
Women with PCOS face many health risks, but exercise, a healthy diet, and weight management can help.
research Activation of Nuclear Factor κB in Response to Cream Ingestion Is Related to Ovarian Androgen Hypersecretion in Polycystic Ovary Syndrome
Eating cream can increase ovarian androgen production in women with Polycystic Ovary Syndrome, which is not related to obesity.
research New Potential Chemotherapy for Ovarian Cancer: Combined Therapy with WP 631 and Epothilone B
The new chemotherapy combination of WP 631 and Epothilone B shows enhanced effectiveness against ovarian cancer but requires more research on its safety.
research ST14 Interacts With TMEFF1 and Is a Predictor of Poor Prognosis in Ovarian Cancer
High levels of ST14 and TMEFF1 proteins in ovarian cancer are linked to worse patient outcomes and may be a new treatment target.
research Managing Acne in Individuals with Polycystic Ovarian Syndrome
Effective acne management in PCOS includes hormone therapy, metformin, isotretinoin, weight loss, diet, exercise, and personalized treatment plans.
research Docetaxel and Oxaliplatin in the Second-Line Treatment of Platinum-Sensitive Recurrent Ovarian Cancer: A Phase II Study
Docetaxel and oxaliplatin are effective and have manageable side effects for recurrent platinum-sensitive ovarian cancer.
research Inositol Versus Metformin Administration in Polycystic Ovarian Disease Patients
Inositol was more effective than metformin in improving menstrual cycles and pregnancy rates in PCOS patients.
research Dihydrotestosterone Induces p27 Degradation via Direct Binding with SKP2 in Ovarian and Breast Cancer
Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.
research Fabrication and In Vitro Evaluation of Silk Fibroin-Folic Acid Decorated Paclitaxel and Hydroxyurea Nanostructured Lipid Carriers for Targeting Ovarian Cancer Cells: A Double Sword Approach
The new drug carriers show promise for better targeting and treating ovarian cancer.
research Hirsutism
Hirsutism is excessive male-pattern hair growth mainly caused by ovarian hormones, and severe cases may require costly treatment with side effects.
research Metformin Effects on Blood Levels of Gremlin-1 in Polycystic Ovarian Women
Metformin lowers gremlin-1 and improves insulin resistance in women with PCOS.
research Book Review
The book provides a clear overview of PCOD and is recommended for medical trainees and clinicians, but may lack depth for advanced researchers.
research Evaluation of Short-Term Efficacy and Long-Term Oncological Outcomes of Different Paclitaxels Plus Platinum Regimens in the Treatment of Serous Ovarian Cancer—A Real World Study
The Li-Pa/Ca and Do/Ca chemotherapy regimens for serous ovarian cancer showed better short-term and long-term results than the Pa/Ca regimen.
research A Case of Leydig Cell Virilizing Tumor of the Ovary
Surgery on a 68-year-old woman with an ovarian tumor led to reduced hirsutism and normal testosterone levels.
research An Exploration into the Management and Diagnosis of Polycystic Ovarian Syndrome by Complementary and Alternative Medical Practitioners in the eThekwini Area
CAM practitioners in the eThekwini area are exploring ways to manage and diagnose Polycystic Ovarian Syndrome.