December 2025 in “International Journal of Molecular Sciences” This review examined 40 studies on exosome-based therapies for alopecia areata, reporting significant hair regrowth and improvements in hair count, length, and thickness, but highlighted the need for standardized methodologies and robust RCTs before clinical application.
November 2025 in “JPRAS Open” This study found that while exosome therapy shows promise for treating AGA, AA, and CIA, its integration into routine practice will depend on rigorous clinical trials and standardized manufacturing and regulatory practices to ensure safety and reproducibility.
September 2025 in “Medicine” This study found that male patients with androgenetic alopecia exhibited signs of increased arrhythmia risk, such as higher P-wave dispersion and lower corrected QT interval on ECG, suggesting potential benefits from closer cardiac monitoring.
January 2025 in “International Journal of Biological Macromolecules” This study found that decorin treatment significantly enhances dermal papilla cell proliferation, promoting hair follicle growth by influencing the SMAD3/TGF-β signaling pathway through exosomal miR-129–2-3p, which may aid in novel strategies for treating hair disorders and enhancing wool production.
July 2024 in “Indian Journal of Dermatology Venereology and Leprology” This study found that specific PITX2 gene variants are significantly associated with higher risk of androgenetic alopecia in males, highlighting important genetic and environmental interactions influencing its development.
May 2024 in “Molecules/Molecules online/Molecules annual” This narrative review reports that well-selected plant extracts and their active compounds may improve hair health by promoting hair growth and preventing hair loss, potentially aiding in developing targeted therapies for alopecia.
February 2024 in “Clinical, Cosmetic and Investigational Dermatology” This study reports a solid causal relationship between increased serum levels of ApoB, LDL, and VLDL and an elevated risk of androgenic alopecia.
June 2023 in “Antioxidants” This study found that lipids extracted from Schizochytrium sp. significantly enhanced the proliferation and survival of dermal papilla cells under oxidative stress, reduced reactive oxygen species, inhibited ferroptosis, and promoted antioxidant genes, which improved hair growth in experimental settings, suggesting a potential treatment for alopecia.
April 2023 in “Nigerian Journal of Clinical Practice” In this study, androgenetic alopecia in Nigerians was associated with dyslipidemia, alcohol intake, and sedentary lifestyle, with severity linked to age, systolic blood pressure, and obesity.
September 2022 in “International Journal of Health Sciences (IJHS)” This study examined the relationship between zinc status and DNA oxidative damage in patients with hair loss in Duhok, Kurdistan Region-Iraq, highlighting the potential role of zinc deficiency in hair loss.
June 2022 in “Authorea (Authorea)” This review discusses various methods for delivering CRISPR/Cas9 for gene editing in vitro and in vivo, highlighting delivery as a major challenge but reports no new experimental results.
July 2021 in “Journal of Dermatology and Dermatologic Surgery” This study suggests an association between metabolic syndrome and androgenic alopecia severity, though this association was not statistically significant.
This review discusses the role of the Wnt/β-catenin pathway in hair follicle development and how natural products that activate this signaling could be used to treat hair loss, but it reports no new experimental results.
January 2022 in “Surgical and Cosmetic Dermatology” This study found a significant correlation between androgenic alopecia and metabolic syndrome, suggesting individuals with alopecia have higher odds of metabolic syndrome.
July 2015 in “Egyptian Journal of Dermatology and Venereology” This study concluded that patients with androgenetic alopecia may have a higher risk of cardiovascular diseases compared to people without this condition.
37 citations
,
January 1986 in “Carcinogenesis” This study found that TPA treatment transiently induces high levels of ODC in mouse epidermal cells, particularly around hair follicles, with localization reduced by retinoic acid or cycloheximide pretreatment.
19 citations
,
January 2020 in “Journal of Biophotonics” This study found that using a PEG-400/oleic acid mixture as an optical clearing agent enhanced the detection depth of particles in skin without causing dehydration, based on tests in rats and further testing in vivo.
4 citations
,
February 2011 in “Annals of internal medicine” This article discusses polycystic ovary syndrome, outlining its prevalence, diagnostic criteria, and the progress made in understanding this underdiagnosed condition, but reports no new clinical findings.
4 citations
,
November 2023 in “Acta obstetricia et gynecologica Scandinavica” In this guideline update, researchers emphasized refining diagnostic criteria for polycystic ovary syndrome using ultrasound or hormone levels, while highlighting a healthy lifestyle's importance without specific diet recommendations, and reviewed treatments with a focus on comorbidities and pregnancies from a Nordic standpoint.
January 2010 in “China Animal Husbandry & Veterinary Medicine” This study suggests that RORα, RORβ, and RORγ mRNA expression in cashmere goat skin is related to different stages of hair follicle development, indicating a possible role in cycled cashmere growth.
1 citations
,
October 2023 in “The Laryngoscope” In this study, single-port endoscopic removal of forehead osteoma in adult patients showed complete tumor removal with excellent cosmetic results, highlighting otolaryngologists' expertise in minimally invasive techniques and achieving low surgical morbidity.
January 2020 in “Case reports in endocrinology” This case report describes a 29-year-old female with resistant polycystic ovary syndrome who experienced symptom relief following a unilateral oophorectomy.
January 2016 in “e-Oftalmo CBO Revista Digital de Oftalmologia” This review discusses central serous chorioretinopathy, detailing its etiology, associated factors, diagnostic imaging, and therapeutic options, but provides no new clinical findings.
292 citations
,
April 2024 in “Nature Reviews Disease Primers” Early diagnosis and treatment of PCOS are crucial to reduce health risks and costs.
May 2023 in “International Journal of Home Science” This survey reported that 95% of respondents were aware of polycystic ovary syndrome, highlighting a high level of awareness about PCOS among the participants.
October 2022 in “Journal of Pediatric and Adolescent Gynecology” This case study observed that unilateral oophorectomy may improve severe hyperandrogenism in adolescents with PCOS, even when imaging and SVS do not indicate neoplasm.
56 citations
,
April 2015 in “American journal of medical genetics. Part A” This study reports on eight previously unpublished cases of Bohring-Opitz syndrome with ASXL1 mutations, suggesting the importance of screening for Wilms tumors in these patients.
October 2023 in “Journal of the Endocrine Society” In this study, distinct androgen excess subtypes were identified in women with PCOS, with the adrenal androgen excess cluster showing significantly higher rates of insulin resistance and type 2 diabetes, suggesting 11-oxygenated androgens as potential drivers of metabolic risk.
31 citations
,
September 1999 in “Molecular Carcinogenesis” This study in a transgenic mouse model found that repressing overexpression of ornithine decarboxylase reduced papilloma development, indicating its role in tumor promotion sensitivity.