15 citations,
May 1997 in “Annals of Internal Medicine” Tamoxifen caused hair loss in a 52-year-old woman.
96 citations,
December 2018 in “Immunity” Targeting TGFβ can improve skin immunity in older people.
14 citations,
November 2020 in “International Journal of Biological Macromolecules” Mushroom-based scaffolds help heal skin wounds and regrow hair.
47 citations,
March 2022 in “Frontiers in cellular and infection microbiology” Changes in skin microbes play a role in some skin diseases and could lead to new treatments.
127 citations,
January 2015 in “Journal of Biological Rhythms” The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
44 citations,
December 1991 in “Annals of the New York Academy of Sciences” EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
1 citations,
June 2006 in “Experimental dermatology” The conclusion suggests that early signs of hidradenitis suppurativa may start in the hair follicle, with genetic and immune factors playing a role, highlighting the need for more research on the hair follicle's immune system.
2 citations,
February 2019 in “Journal of Investigative Dermatology” Higher levels of the DP2 receptor may lead to hair loss.
April 2018 in “Journal of Investigative Dermatology” Stabilizing HIF1A in hair follicles increases glycolysis, which may help reduce oxidative stress and support hair growth.
June 2017 in “Journal of the American Academy of Dermatology” Plucked hair can help diagnose pemphigus vulgaris early.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers made a detailed map of gene activity for different parts of human hair follicles to help create targeted hair disorder treatments.
1 citations,
July 2016 in “Livestock science” Nerve growth factor helps cashmere goat hair cells grow and is more active during the hair growth phase.
1 citations,
January 2012 in “International journal of trichology” Sheep hair follicle cells can grow a lot but need the dermal papilla to do so.
8 citations,
January 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Growth hormone is important for regulating human hair growth.
1 citations,
October 2022 in “Scientific reports” Nestin identifies specific progenitor cells in hair follicles that can become outer root sheath cells.
10 citations,
April 2022 in “Critical reviews in food science and nutrition” Skin odorant receptors respond to flavors and could be targeted to improve skin health and treat diseases.
30 citations,
February 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Plet-1 protein helps hair follicle cells move and stick to tissues.
22 citations,
January 2012 in “International Journal of Trichology” Miniaturized hairs stay connected to muscle in alopecia areata, allowing possible regrowth, but not in androgenetic alopecia.
September 2022 in “Journal of Theoretical Biology” Hair follicles can regenerate after radiation damage but not during a specific growth phase.
45 citations,
August 2013 in “Facial Plastic Surgery Clinics of North America” Using sharp tools and the right techniques in hair transplant surgery leads to less damage to hair follicles.
November 2022 in “Journal of Investigative Dermatology” Growth hormone-releasing hormone (GHRH) boosts hair growth and human scalp hair follicles have their own growth hormone system.
15 citations,
July 2004 in “Journal of morphology” Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.
14 citations,
January 2009 in “Experimental Dermatology” Hair sheds gradually from the follicle, with readiness to shed indicated by less attachment material.
13 citations,
January 2002 in “Biochemical and biophysical research communications” Interferon β from hair cells stops the growth of other hair cells.
10 citations,
October 1993 in “Archives of dermatological research” Vitamin D compounds may help treat psoriasis by promoting skin cell differentiation.
June 2023 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Impaired ABCA5 activity disrupts cholesterol balance in hair follicle cells, affecting hair growth.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” JAK inhibitors help hair growth by boosting beta-catenin activity in hair root cells.
17 citations,
February 2015 in “International Journal of Molecular Sciences” A special mix from certain skin cells can help hair grow by making hair root cells grow faster and activating growth signals.
4 citations,
June 2022 in “Journal of Cosmetic Dermatology” Multi-peptide factors from fibroblasts may stimulate hair growth by increasing growth factors and β-catenin in hair cells.
1 citations,
August 2022 in “International Journal of Molecular Sciences” FGF12 is important for hair growth and could be targeted for hair loss treatment.