Green Fabrication of Seedbed-Like Flammulina Velutipes Polysaccharides-Derived Scaffolds Accelerating Full-Thickness Skin Wound Healing Accompanied by Hair Follicle Regeneration

January 2021 in “ International Journal of Biological Macromolecules ”

Feixiang Chen, Qiang Zhang, Ping Wu, Yanan Zhao, Xiaotong Suo, Ao Xiao, Meifang Ke, Xiaohua He, Zan Tong, Yun Chen

Flammulina velutipes polysaccharides scaffolds skin wound healing hair follicle regeneration FPS/NaOH microenvironment responsive cells mushroom polysaccharides wound healing hair regrowth

TLDR Mushroom-based scaffolds help heal skin wounds and regrow hair.

The study investigated the use of Flammulina velutipes polysaccharides-derived scaffolds (FPDSS) for skin wound healing and hair follicle regeneration. The results showed that FPDSS could provide a favorable microenvironment for skin tissue regeneration and hair follicle regeneration. Among the FPDSS groups, the FPS/NaOH group had the best wound-healing capacity and maximum number of responsive cells in the microenvironment. The study suggests that FPDSS, especially FPS/NaOH, can promote wound healing and hair follicle regeneration.

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