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    Glossary Organ Regeneration

    process of naturally repairing or regrowing damaged organs

    Organ regeneration refers to the process by which damaged or lost organs are naturally repaired or regrown by the body. This involves the activation of stem cells and other cellular mechanisms to replace the missing tissues, restoring the organ's original structure and function. In humans, this capability is limited, but research in regenerative medicine aims to harness and enhance these processes for therapeutic purposes.

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    1. Nerve dependence in tissue, organ, and appendage regeneration Trends in Neurosciences · 2012 · 228 citations
    2. Macrophages and fibroblasts during inflammation and tissue repair in models of organ regeneration Regeneration · 2017 · 201 citations
    3. Skin and hair: models for exploring organ regeneration Human Molecular Genetics · 2008 · 35 citations
    4. Organ regeneration based on developmental biology: past and future Current Opinion in Genetics & Development · 2018 · 21 citations
    5. The global regulatory logic of organ regeneration: circuitry lessons from skin and its appendages 2021 · 9 citations
    6. Organ Regeneration Methods in molecular biology · 2017 · 3 citations
    7. Harnessing mesenchymal aggregation for engineered organ‐level regeneration: Recent progress and perspective Aggregate · 2023
    8. Organ-Level Quorum Sensing Directs Regeneration in Hair Stem Cell Populations Cell · 2015 · 236 citations
    9. Hair organ regeneration via the bioengineered hair follicular unit transplantation Scientific Reports · 2012 · 66 citations
    10. Scaffold-based developmental tissue engineering strategies for ectodermal organ regeneration Materials Today Bio · 2021 · 22 citations
    11. Fully functional hair follicle organ regeneration using organ-inductive potential stem cells with an accessory mesenchymal cell population in an in vitro culture system Biochemical and Biophysical Research Communications · 2026
    12. Diverse mechanisms for endogenous regeneration and repair in mammalian organs Nature · 2018 · 172 citations
    13. Developmental Plasticity of Patterned and Regenerating Oral Organs Current Topics in Developmental Biology · 2015 · 5 citations
    14. Roles of Hippo signaling pathway in size control of organ regeneration Development Growth & Differentiation · 2015 · 37 citations
    15. Regeneration of a bioengineered 3D integumentary organ system from iPS cells Nature protocols · 2019 · 12 citations
    16. Tooth tissue and organ regeneration using stem cells Inflammation and Regeneration · 2013 · 4 citations
    17. Hyperinnervation inhibits organ-level regeneration in mammalian skin Cell · 2026
    18. Regeneration of complex oral organs using 3D cell organization technology Current Opinion in Cell Biology · 2017 · 8 citations
    19. Mammalian Fetal Organ Regeneration 2005 · 32 citations
    20. Functional ectodermal organ regeneration as the next generation of organ replacement therapy Open Biology · 2019 · 8 citations
    21. Functional salivary gland regeneration by transplantation of a bioengineered organ germ Nature Communications · 2013 · 165 citations
    22. Functional lacrimal gland regeneration by transplantation of a bioengineered organ germ Nature Communications · 2013 · 256 citations
    23. Design of an artificial skin. IV. Use of island graft to isolate organ regeneration from scar synthesis and other processes leading to skin wound closure Journal of Biomedical Materials Research · 1998 · 13 citations
    24. Wnt Signaling Across Adult Skin Mini-Organs: Interfollicular Epidermis, Hair Follicle, and Nail—Implications for Disease and Regeneration International Journal of Molecular Sciences · 2026
    25. Parallels in signaling between development and regeneration in ectodermal organs 2022 · 8 citations
    26. Physiological Regeneration of Skin Appendages and Implications for Regenerative Medicine Physiology · 2012 · 60 citations
    27. Hair Follicle Regeneration by Transplantation of a Bioengineered Hair Follicle Germ Methods in molecular biology · 2016 · 6 citations
    28. Development and Prospective Applications of 3D Membranes as a Sensor for Monitoring and Inducing Tissue Regeneration Membranes · 2023
    29. Functional Hair Follicle Regeneration Springer eBooks · 2017
    30. Ectodermal Organ Stem Cells: Morphogenesis, Population Regenerative Behavior, and Evo-Devo 2013 · 1 citations