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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.

Vitamin D3 affects cell differentiation in specific skin areas.

Adult mice can grow new hair from skin wounds.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.

Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

Finasteride may help some women with hair loss, but better options exist.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.

A special microbe helps plants absorb rock phosphate by growing on their root hairs.

Hedgehog signaling is crucial for mammary gland development over hair follicles.

Minoxidil promotes hair regrowth in early baldness stages and prevents baldness in non-bald scalps.

Hair in mammals likely evolved from glandular structures, not scales.

EDA and EDAR are important for hair follicle development in cashmere goats and affect other related genes.

Overexpressing SIMK in alfalfa boosts root hair growth, nodule clustering, and shoot biomass.

Researchers created specific antibodies that detect a protein important in development and various conditions, and can be used for research and diagnosis.

150 kHz electromagnetic radiation might help improve PCOS in rats.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

A fungus called Epidermophyton floccosum can cause scalp infections.

Activating TRPA1 reduces scarring and promotes tissue regeneration.

Fish oil improves skin health in people with diabetes and high cholesterol.

Photobiomodulation helps reduce pain, lessen inflammation, heal wounds, and can be used in skin treatments. It also boosts hair growth in women with hair loss and may help fight microbes and prevent respiratory issues in COVID-19.

Stem cell research and regenerative medicine have made significant advancements in treating various diseases and conditions.

Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.

Understanding skin patterns can help us learn about skin diseases and their treatments.