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Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Monochromatic light devices, especially the 308-nm excimer laser, are promising for treating alopecia areata but more research is needed.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

Sp6 promotes tooth development by reducing follistatin levels.

Lupus can look like hair loss from alopecia areata but needs different treatment.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Herbal alternatives like saw palmetto and green tea may offer safe, effective treatment for hormonal hair loss.

Autoimmune liver diseases are likely linked to certain skin conditions like vitiligo and psoriasis.

Testosterone improves mood and thinking skills; finasteride has no effect.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Polycystic Ovary Syndrome can cause hair loss and skin issues, and early treatment is important for preventing complications.

The document concludes that it's important to understand the placebo effect when evaluating the effectiveness of treatments in medical trials.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Mesotherapy might help reduce fat in specific areas for those close to their ideal weight, but more research and care are needed to ensure safety.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Using microneedles before applying eflornithine cream can make it more effective at stopping hair growth.

Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

The study aims to find the best treatment for central serous chorioretinopathy by comparing various options.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.