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The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Herbal alternatives like saw palmetto and green tea may offer safe, effective treatment for hormonal hair loss.

Autoimmune liver diseases are likely linked to certain skin conditions like vitiligo and psoriasis.

Testosterone improves mood and thinking skills; finasteride has no effect.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Polycystic Ovary Syndrome can cause hair loss and skin issues, and early treatment is important for preventing complications.

The document concludes that it's important to understand the placebo effect when evaluating the effectiveness of treatments in medical trials.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Mesotherapy might help reduce fat in specific areas for those close to their ideal weight, but more research and care are needed to ensure safety.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Using microneedles before applying eflornithine cream can make it more effective at stopping hair growth.

Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

The study aims to find the best treatment for central serous chorioretinopathy by comparing various options.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.

Metabolic syndrome linked to female hair loss; waist size and high blood pressure important factors.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Looking at skin can help find and treat serious diseases early.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.