1 citations
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September 2025 in “Plant Science Today” This study reported that an herbal formulation containing aqueous extracts of Hibiscus rosa sinensis and Vitex negundo demonstrated promising antimicrobial, antioxidant, anti-inflammatory, and cytotoxic activities, indicating potential health benefits and applications in managing autoimmune diseases.
54 citations
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July 1994 in “Journal of Dermatological Science” This study found that topical application of FK506 stimulated hair growth in animals, which may occur independently of its immunosuppressive effects, though its effect on human hair growth remains unclear.
165 citations
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January 2014 in “Dermatology Research and Practice” This review discusses the various dermatological applications of zinc, including its use in treating infections, inflammatory dermatoses, pigmentary disorders, and neoplasias, and reports no new clinical findings.
5 citations
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January 2014 in “Hospital pharmacy” This case report suggests that frequent application of diphenylcyclopropenone 2% solution to the scalp for alopecia areata may lead to scalp angioedema.
69 citations
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February 1987 in “Archives of Dermatology” This case report describes the topical application of cyclosporine in a man with alopecia universalis, which showed hair regrowth after 10 months of daily use, except where limited by a congenital nevus.
343 citations
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December 2008 in “Endocrine Reviews” This review discusses the various evidence-based and potential applications of metformin in treating and preventing symptoms and complications associated with polycystic ovary syndrome but reports no new clinical results.
November 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study found that both oral and topical formulations of VISPOTM, a saw palmetto oil, significantly reduced hair fall and increased hair density in subjects with androgenetic alopecia, with no serious adverse effects observed.
15 citations
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March 1997 in “International Journal of Dermatology” This article discusses the potential use of 5α-reductase inhibitors in dermatology and reports no new clinical results; the authors suggest further exploration of their dermatological applications.
12 citations
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June 2023 in “JAMA network open” In this study of seven randomized clinical trials, JAK inhibitors were associated with improved hair regrowth outcomes in alopecia areata patients compared to placebo, with oral administration being more effective than external application, though longer trials are needed to confirm safety and effectiveness.
11 citations
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January 2018 in “International journal of trichology” This article reviews valproate's impact on hair health, reporting both hair loss linked with oral use and early signs of hair regeneration from topical applications, without presenting new clinical results.
5 citations
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July 2013 in “InTech eBooks” This book reviews the role of skin biopsy in diagnosing and treating various dermatological diseases, discussing site selection and applications for conditions like alopecia and pemphigus, but reports no new clinical results.
2 citations
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May 2022 in “Research Square (Research Square)” This study demonstrates that the amino-terminally shortened KGF-1 variant with 135 residues maintains biological activity, suggesting it may serve as an alternative to the original KGF-1 for certain therapeutic applications.
1 citations
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November 2021 in “Ultrasonography” This study found that applying low-intensity ultrasound enhanced hair growth on the treated area of mice with androgenic alopecia, potentially by affecting the action of finasteride.
November 2025 in “Skin Appendage Disorders” This study reviewed 16 studies on Ayurvedic treatments for hair disorders, indicating that they commonly involve oral herbal medications, topical applications, and scalp manipulation, and report clinical outcomes for conditions like alopecia areata and telogen effluvium.
January 2015 in “Elsevier eBooks” This chapter reviews the use of liposomes and cyclodextrins to improve the delivery and effectiveness of the peptide angiotensin-(1-7) in various therapeutic applications and reports no new experimental results.
August 2021 in “Annales pharmaceutiques françaises” This study used computer simulations to evaluate the absorption of oral and topical finasteride for treating androgenetic alopecia, finding that topical applications resulted in lower plasma concentrations, suggesting potential viability as a treatment option.
5 citations
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April 2025 in “Journal of the American Academy of Dermatology” This source provides an overview of expert practices for using topical and low-dose oral minoxidil in treating hair loss, highlighting how dermatologists apply existing literature to ensure safe and effective treatment.
3 citations
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October 2009 in “Iranian Journal of Basic Medical Sciences” This study suggests that the methanol extract of Buxus wallichiana has promising antioxidant properties and may promote hair growth, with varying effectiveness depending on the dosage and application form.
42 citations
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July 2021 in “Frontiers in Cell and Developmental Biology” This review examines the regeneration capabilities of skin, oesophagus, and oral mucosa, highlighting the oral mucosa's unique scarless healing properties and the potential of cell therapy to improve scar reduction in wound healing.
4 citations
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January 2022 in “Current pharmaceutical design” This review discusses the benefits and applications of microsponges delivery systems in drug delivery, particularly for topical treatments, and reports no new clinical findings.
December 2025 in “International Journal of Molecular Sciences” In this study, orally administered Centella asiatica extract, standardized for asiaticoside content, significantly improved skin barrier function, elasticity, and reduced signs of UVB-induced photoaging in hairless mice, highlighting its potential as a nutricosmetic for skin health.
39 citations
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April 2011 in “Recent Patents on Drug Delivery & Formulation” This review discusses various applications of nanoemulsions in drug delivery and reports no new clinical results; it highlights the patents that cover these applications.
6 citations
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June 2022 in “Dermatologic Therapy” This review discusses the biological effects of honokiol for treating skin diseases and reports no new clinical results; the authors recommend further exploration of topical applications.
This review highlights the potential of microneedles as a pediatric-friendly method for delivering proteins, vaccines, and diagnostics transdermally, noting their ability to penetrate the skin's barrier and suggesting future applications in other parts of the body.
February 2026 in “Scientific Reports” This preclinical study found that Mesenchymal Stem Cell-derived Conditioned Media formulations were safe and effective in rat and mouse models for treating chemotherapy- and radiation-induced oral mucositis, demonstrating improved tissue regeneration and healing, most notably at higher concentrations.
March 2025 in “International Journal of Trichology” This case report describes a 14-year-old female patient with monilethrix who developed female androgenetic alopecia at age 23, and found that oral minoxidil treatment improved her androgenetic alopecia while leaving the underlying structural hair anomalies of monilethrix unchanged.
September 2024 in “Medical Sains Jurnal Ilmiah Kefarmasian” This review summarizes the potential of nanostructured lipid carriers in drug delivery systems, highlighting their promise in enhancing the stability and skin penetration of anti-aging cosmetics.
January 2024 in “Journal of dermatology and skin science” In this study, researchers found that applying topical aprepitant, which blocks substance P receptors, significantly reduced facial dermatitis and hair loss in rats experiencing erlotinib-induced skin side effects, highlighting the neurogenic inflammation's role and the protective effect of ROS inhibition.
8 citations
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April 1988 in “Journal of endocrinological investigation” This study found that topically administered spironolactone in healthy volunteers resulted in no detectable systemic absorption or changes in related hormone levels over 72 hours, indicating local effect only.
2 citations
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October 2020 in “Más dermatología” Choose between topical and oral minoxidil for hair growth based on personal tolerance and side effects.