research Abstracts from the ASA 40th Annual Meeting
HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.
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research The Role of Histone Demethylases in Disease
Histone demethylases play a key role in the development of many diseases and may be targets for treatment.
research Physiological Functions of PP2A: Lessons from Genetically Modified Mice
Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.
research Investigation on Antimicrobial, Antioxidant, and Anti-Cancerous Activity of Agaricus Bisporus Derived Beta-Glucan Against Cervical Cancer Cell Line
Agaricus bisporus derived β-Glucan could be an effective cervical cancer treatment with antimicrobial and antioxidant properties.
research Principles of Chemotherapy
Chemotherapy is crucial for treating gynecological cancers but requires careful management due to severe side effects.
research Hirsutism: From Brazil to a Place Near You
No treatment fully stops excessive hair growth in women, but various methods can help manage it effectively.
research Recent Advances in the Structural Design of Photosensitive Agent Formulations Using Soft Colloidal Nanocarriers
New nanocarriers improve drug delivery for disease treatment.
research Molecular Mechanisms of Viral Oncogenesis in Humans
Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
research Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection
Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
research The Antiandrogen Enzalutamide Downregulates TMPRSS2 and Reduces Cellular Entry of SARS-CoV-2 in Human Lung Cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
research Dihydrotestosterone Induces Proliferation, Migration, and Invasion of Human Glioblastoma Cell Lines
Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.
research Colon Cancer Stem Cells: Promise of Targeted Therapy
Targeting colon cancer stem cells might lead to better treatment results.
research Other Questions on Basaloid Follicular Hamartoma
Basaloid follicular hamartoma's appearance can be similar to other skin conditions, and diagnosis should consider both the look and behavior of the tumor.
research Eruptive Vellus Hair Cysts: An Original Case Occurring in Twins
Twins had rare skin cysts likely due to genetics.
research Telogen Effluvium: The Debate on Catagen and Hair Shedding Mechanisms
The debate focuses on the role of catagen and hair shedding mechanisms in telogen effluvium.
research Compounded Topical Preparations in Plaque Psoriasis: Still a Place for It in 2018?
Compounded topical preparations should be used with caution for severe psoriasis and generally come after systemic treatments.
research Telogen Effluvium: A Response
Both parties agree that cell death is important in the hair cycle, but they have different views on the role of the catagen phase and hair shedding.
research Cutaneous Adverse Effects of Targeted Therapies
Targeted cancer therapies often cause serious skin problems that need careful management.
research The Paradox of p53: What, How, and Why?
The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
research Microencapsulated Human Hair Dermal Papilla Cells: A Substitute for Dermal Papilla?
Encapsulated human hair cells can substitute for natural hair cells to grow hair.
research The HPV16 Oncogenes Cause Aberrant Stem Cell Mobilization
HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
research Establishment of SV40T-Transformed Human Dermal Papilla Cells and Identification of Dihydrotestosterone-Regulated Genes by cDNA Microarray
Researchers created a cell line to study hair growth and found specific genes affected by dihydrotestosterone.
research Testosterone- and Cortisol-Secreting Adrenocortical Oncocytoma: An Unusual Cause of Hirsutism
A woman's excessive hair growth was caused by a rare benign tumor in her adrenal gland, which was successfully removed.
research Melatonin Protects Cochlear Hair Cells from Nicotine-Induced Injury Through Inhibiting Apoptosis, Inflammation, Oxidative Stress, and Endoplasmic Reticulum Stress
Melatonin may protect ear cells from damage caused by nicotine.
research Expression and Cellular Localization of Keratinocyte Growth Factor and Its Receptor in Human Hyperplastic Prostate Tissue
KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.
research Innovative Sequence of Docetaxel–Gemcitabine Based on Preclinical Data in the Treatment of Advanced Non-Small Cell Lung Cancer: A Phase I Study
The new chemotherapy combination for advanced lung cancer showed a 35.7% response rate but caused significant side effects.
research Vandetanib-Associated Alopecia Areata in a Patient with Metastatic Medullary Thyroid Cancer
A cancer patient developed a type of hair loss after starting a cancer drug called vandetanib.
research Polyomavirus-Induced Pilomatricomas in Mice: From Viral Inoculation to Tumor Development
Polyomavirus A2 infection in newborn mice caused hair follicle tumors.
research MicroRNA Control of Signal Transduction
MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.
research Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance
Understanding phenotypic plasticity is crucial for developing effective cancer therapies.