47 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This review examines the pathogenesis of premature hair graying and potential treatment avenues, but reports no new experimental outcomes, highlighting ongoing research challenges and hopes for drug development.
47 citations
,
April 2003 in “Journal of dermatological science” This study showed that Thujae occidentalis semen extract inhibited 5alpha-reductase type 2 in laboratory tests and reduced androgen-related hair loss in animal models, suggesting potential use for male pattern baldness.
47 citations
,
May 2002 in “Journal of Cutaneous Medicine and Surgery” This review discusses normal skin changes during pregnancy such as pigmentary and glandular alterations, highlighting the need for physician awareness to avoid unnecessary treatments, and reports no new clinical findings.
45 citations
,
August 2019 in “Dermatologic Therapy” This review discusses the physiopathology of androgenetic alopecia and evaluates various traditional and emerging treatments, reporting no new clinical results but highlighting the need for enhanced treatment strategies.
45 citations
,
February 2018 in “Journal of basic and clinical physiology and pharmacology/Journal of basic & clinical physiology & pharmacology” This review summarizes the ethno-medicinal uses, phytochemical constituents, and biological activities of Acorus calamus, highlighting its potential therapeutic benefits and the importance of further scientific work on this plant.
44 citations
,
March 2020 in “Antibiotics” The researchers reported that carnosic acid and carnosol, extracts from rosemary leaves, specifically inhibit S. aureus virulence expression, suggesting potential topical treatments for atopic dermatitis flares.
44 citations
,
August 2017 in “Food Bioscience” This study found that betasitosterol-loaded nanostructured lipid carriers, when added to butter, improved its nutritional profile and antioxidant properties, maintaining stability over a three-month storage period.
44 citations
,
March 2012 in “Fitoterapia” In this study, germacrone from Curcuma aeruginosa showed anti-androgenic effects by inhibiting 5α-reductase, suggesting its potential as a lead compound for treating androgen-dependent disorders.
42 citations
,
January 2024 in “Frontiers in Endocrinology” This review discusses polycystic ovary syndrome treatments, focusing on the potential benefits and safety of herbs and phytochemicals, and reports no new clinical results.
41 citations
,
July 2015 in “Current Drug Discovery Technologies” This review discusses various plants and herbal formulations traditionally used for hair growth and notes their potential as safer alternatives to synthetic hair loss treatments, but reports no new clinical results.
40 citations
,
August 2018 in “Skin appendage disorders” This review examines complementary and alternative medicine for alopecia and finds limited support from robust clinical trials, highlighting the need for standardized studies to evaluate efficacy and safety.
40 citations
,
January 2010 in “Indian Journal of Dermatology, Venereology and Leprology” This article reviews the role of diet in various skin disorders and suggests that dietary changes may aid in managing certain conditions, though it reports no new clinical findings.
39 citations
,
October 2018 in “Aesthetic surgery journal” This review discusses nonsurgical techniques for facial masculinization and feminization in transgender patients and reports no new clinical findings, utilizing data from analogous procedures in cisgender individuals.
39 citations
,
June 2017 in “Journal of Applied Research on Medicinal and Aromatic Plants” This review examines around 68 plant sources from six major plant families, assessing their scientific rationale and use by the cosmeceutical industry for applications like anti-ageing and sun protection.
39 citations
,
July 2016 in “Biomedicine & Pharmacotherapy” In this animal study, researchers found that cedrol, a constituent from Platycladus orientalis, significantly promoted hair growth in a dose-dependent manner in female C57BL/6 mice, surpassing results from blank control and 2% minoxidil groups over 21 days.
39 citations
,
December 2013 in “Phytotherapy Research” This study found that hydroxysafflor yellow A-rich Carthamus tinctorius extract promoted hair growth and gene expression linked to hair proliferation in both cell cultures and mouse models.
38 citations
,
January 2015 in “Journal of Cosmetic Dermatology” This study found that a 6-month supplementation with omega 3, omega 6, and antioxidants significantly improved hair density and reduced hair loss in women with female pattern hair loss.
38 citations
,
June 2005 in “Contact Dermatitis” This case report describes a patient with an allergic sensitization to minoxidil, indicating that such patients should pursue alternative therapies to treat androgenetic alopecia.
37 citations
,
January 2019 in “Food science & nutrition” This review summarizes various effects of bergamot components on multiple health conditions in humans and animals but reports limitations in their use for stress and anxiety relief in aromatherapy.
36 citations
,
January 2017 in “Journal of Obstetrics and Gynaecology Research” This review discusses the association between vitamin D receptor polymorphisms and polycystic ovary syndrome, noting the need for further research on their impact on the disorder's manifestations.
35 citations
,
January 2018 in “Skin pharmacology and physiology” This study found that nanoemulsion formulations with oleic acid or eucalyptol significantly enhanced the delivery and retention of caffeine through hair follicles and surrounding skin regions.
35 citations
,
June 2017 in “Pharmacognosy Journal” This study found that alkaloids isolated from Eclipta alba leaves showed increasing antimicrobial activity with higher concentrations, particularly against S. aureus and E. coli, suggesting potential for developing antimicrobial agents.
35 citations
,
May 2012 in “Cochrane Database of Systematic Reviews” This review found evidence supporting the effectiveness and safety of topical minoxidil for treating female pattern hair loss, though many included studies were at high risk of bias.
34 citations
,
July 2011 in “Journal of Dermatological Treatment” This study found that a combination of 5% hexane extract of Curcuma aeruginosa and 5% minoxidil slowed hair loss and increased hair growth in men with androgenetic alopecia.
34 citations
,
August 2002 in “British Journal of Dermatology” This study observed that two patients treated with interferon α-2b and ribavirin for chronic hepatitis C experienced complete and reversible straightening of their natural curly hair, which recurred with treatment resumption.
34 citations
,
September 1992 in “Journal of the American Academy of Dermatology” This article provides dermatology residents with essential information on cosmetic use to help manage skin conditions and reactions, without reporting new clinical results.
33 citations
,
August 2006 in “Journal der Deutschen Dermatologischen Gesellschaft” Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.
32 citations
,
January 2021 in “Molecules” This review compiles studies on the antidiabetic potential of plants from the Middle East, particularly from the Asteraceae and Lamiaceae families, but reports no clinical results.
32 citations
,
June 2017 in “Journal of infection/The Journal of infection” This source discusses the diagnosis and treatment of Tinea capitis in children, highlighting that Trichophyton tonsurans is the prevalent cause in the UK and that terbinafine is an effective treatment option.
32 citations
,
August 2015 in “Anais Brasileiros de Dermatologia” This review discusses the side effects and diseases related to hairstyles and hair treatments among black women, highlighting the need for thorough examination by dermatologists, but reports no new clinical results.