May 2026 in “International Journal of Creative and Open Research in Engineering and Management” This review highlights key considerations for developing effective herbal hair oils, focusing on carrier selection, bioactive extraction, and standardization, and suggests incorporating advanced delivery systems like nanoemulsions to improve global manufacturing practices.
191 citations
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November 1959 in “Annals of the New York Academy of Sciences” This article reports electron microscope studies on the structure of hair and wool, but it does not present new clinical findings.
4 citations
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July 2024 in “Animals” In this study on Chinese Tan sheep, researchers discovered a variant of the KRTAP19-5 gene associated with decreased curvature of fine wool fibres, highlighting potential genetic markers for improving wool quality.
2 citations
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February 2025 in “PLoS ONE” This study used TMT-based quantitative proteomics to analyze the development of secondary hair follicles in fetal sheep, revealing increased follicle density and key proteins involved, such as COL1A1 and THBS4, indicating their potential role in wool quality traits.
4 citations
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May 2024 in “Genes” Among Merino × Southdown cross sheep, this study found that certain variants of the KRT81 gene were associated with differences in fleece weight, but not with staple length or fibre diameter traits.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study revealed that tofacitinib may inhibit CD8+ T cell infiltration in alopecia areata by modulating the linoleic acid metabolism-Mg2+ pathway, providing new insights for potential treatments and diagnosis.
2 citations
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February 2025 in “International Journal of Molecular Sciences” This study identified key proteins, such as Sfrp1 and Ppard, involved in the complex and dynamic regulation of yak hair follicle growth and degeneration across different stages, offering insights into yaks' adaptation to highland environments.
22 citations
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February 2002 in “Planta Medica” In this study, osthenol was identified as a highly potent inhibitor of 5alpha-reductase type I in LNCaP cells, significantly outperforming finasteride.
34 citations
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July 2018 in “Veterinary Dermatology” This study established a 3D in vitro culture system of canine keratinocyte organoids to study epidermal function and address skin disorders in dogs, though additional growth factors are needed for hair follicle development.
April 2018 in “Journal of Investigative Dermatology” This study suggests that human hair follicles may operate their own Cori cycle, synthesizing glycogen from lactate under conditions of lactic acidosis.
August 2013 in “Han'gug saengmul gonghag hoeji/KSBB journal” This study found that callus extracts from apple 'Hirosaki' may improve collagen synthesis, hair follicle cell proliferation, and possess significant anti-inflammatory properties.
April 2025 in “Frontiers in Genetics” This study found that integrating breed-specific BOA and SNP-based models helps reveal the genetic factors involved in thermotolerance traits in beef cattle, enhancing insights into thermoregulation and potentially improving cattle's heat resilience.
2 citations
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January 2022 in “BioMed Research International” This study suggests that Gujian oral liquid may reduce osteoarthritis symptoms by regulating inflammation and catabolism through the TNF-α/NF-kappa B signaling pathway, as confirmed by both in vivo and in vitro experiments.
7 citations
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February 2017 in “Open veterinary journal” This study suggests that deficiencies in certain amino acids, like taurine and tryptophan, in artificial milk formulas may contribute to skin and eye problems in Bengal tiger cubs.
September 2026 in “Scientific Reports” This study discovered a conserved "fiber-like-motif" of melanosomes aligned in hair across various mammalian species, shedding light on the internal structure that influences hair's thermal and mechanical properties.
March 1985 in “Journal of the American Academy of Dermatology” This research found that topical minoxidil may promote hair regrowth in alopecia areata by stimulating hair follicle epithelium and suppressing certain immune responses, with potential contributions from its vasodilatory effects.
2 citations
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July 2023 in “Plant Disease” In this study, researchers examined 120 inbred maize lines infected with Fusarium graminearum, discovering that some demonstrated significant resistance to stalk rot, correlated with specific gene pathways. This highlights potential genes and pathways for enhancing disease resistance in maize.
January 2024 in “Collagen and leather” This study observed that using an environmentally friendly bovine milk permeate effectively and cleanly removes wool from sheepskins without harming the skin, and results in smoother leather compared to traditional chemical methods.
10 citations
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May 2016 in “bioRxiv (Cold Spring Harbor Laboratory)” This study observed that differences in the expression of genes related to lipid metabolism may play a major role in determining wool fiber diameter in sheep.
October 2024 in “Scientific Reports” This research observed that oxytocin receptor agonists WAY267464 and LIT001 increased hair growth-related gene expression in human dermal papilla cells and significantly promoted hair follicle sprouting in vitro, suggesting their potential as hair growth agents targeting OXTR for alopecia treatment.
This study developed a natural hair dye using Coreopsis tinctoria Nutt. extract, finding that it produced yellow to dark brown colors depending on the treatment, with ferrous lactate enhancing dye performance and color stability after washing.
59 citations
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January 2021 in “Genes” This study reports identifying 12 candidate genes potentially involved in regulating hair follicle development in cashmere goats, which could contribute to improving cashmere production.
1 citations
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September 2025 in “Molecules” This study comparatively evaluated different extraction techniques for Schinus terebinthifolius Raddi leaf extracts and found that conventional extraction with ethanol yielded the highest antioxidant activity and beneficial effects on skin cell viability, supporting its potential use in sustainable cosmeceutical formulations targeting skin aging.
7 citations
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September 2024 in “BMC Genomics” In this study, whole-genome sequencing of Lanping black-boned sheep identified ERBB4 and ROR1 genes as potentially important in their distinctive hyperpigmentation, enhancing understanding of their genetic evolution from Lanping normal sheep.
January 2017 in “한국약용작물학회지” This study suggests that 70% ethanol extracts from certain medicinal plants may promote hair growth and be useful for developing hair care products.
This study investigated the expression of KRTAP6 gene family in Gansu Alpine fine-wool sheep, finding significant expression during the anagen phase and a negative correlation between KRTAP6-1 and KRTAP6-5 expressions with wool fiber diameter and strength.
24 citations
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June 1999 in “Mechanisms of Development” This study found that ornithine decarboxylase expression is linked to cell proliferation and differentiation in hair follicle development and growth.
1 citations
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January 2021 in “Processes” This study adapted a method for culturing melanocytes from human hair follicles to horses, successfully creating partially melanotic equine melanocytes, potentially advancing hair follicle biology research across species.
14 citations
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January 2006 in “Skin pharmacology and physiology” This study found that procyanidin oligomers from apples and barley may stimulate hair growth by promoting hair epithelial cell proliferation and protecting them from apoptosis via MEK activation in a murine model.
13 citations
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December 2019 in “Nutrients” In human follicular cells, this study found that an Annurca apple-based dietary supplement may stimulate the production of hair keratins, suggesting potential benefits for hair growth.