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This review explores the interactions between the skin, peripheral nervous system, and immune system and reports no new results; the authors highlight the importance of understanding these connections for various skin conditions.

In this study involving a mouse model, researchers reported that intranasal delivery of protein-based CRISPR/dCas9 nanoparticles targeting the gene *Sirt1* reduced cerebral edema and increased survival following ischemic stroke, with no significant toxicity observed.

This compilation details various potential side effects and interactions of vitamin A, but it reports no new research findings.

This report describes a case where a 44-year-old male treated with vorasidenib for diffuse low-grade gliomas developed unexpected hair growth, including in areas of severe hair loss, after one month, highlighting a previously undocumented side effect.

This review highlights the potential of spanlastics, a new type of drug delivery system, to enhance drug administration by offering better deformability and stability compared to other nanocarriers, potentially improving targeted drug delivery across various applications.

This study found that nanodiamonds of various sizes can penetrate different layers of murine skin in vitro, reaching hair follicle niches, and may be suitable for multimodal imaging applications.

This study identified specific profiles and courses of adverse events associated with boron neutron capture therapy for head and neck cancer, suggesting differences based on the beam incidence site.

The researchers reported that using Natesto® testosterone gel improved erectile function and mood in hypogonadal men over a 90-day period.

This review discusses the progress and challenges in delivering CRISPR/Cas9 systems for in vivo genome editing, highlighting current methods and opportunities for future therapeutic applications.

Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.

This study reported that imaging characteristics of sebaceous nevus vary significantly by age group, revealing dynamic developmental changes that can be effectively identified through dermoscopy and reflectance confocal microscopy, offering noninvasive diagnostic potential.

This review discusses how liposomes and niosomes can enhance drug penetration in topical delivery systems and emphasizes the importance of their specific composition, size, and type, but it reports no new results.

This study found that the PVP protocol, combining Peptichemio, vincristine, and 6-methylprednisolone, resulted in remission for diffuse non-Hodgkin's lymphomas with moderate side effects.

This review systematically examined recent advancements in spironolactone-loaded nanocarriers, revealing that lipid and vesicular nanoparticles enhance bioavailability and skin penetration for treating androgen-dependent disorders, but highlighted the need for further clinical studies to optimize their use.

This study found that Spironolactone-loaded ethosomal gels provided superior skin permeation and deposition compared to niosomal gels in rabbit skin, suggesting that ethosomal gels could be a promising formulation for further clinical studies on treating androgenic alopecia.

In this study, researchers developed a hybrid deep learning model called ScalpViT that accurately diagnosed scalp diseases with 94.3% accuracy, surpassing existing methods like ResNet-50 and EfficientNet-B3, and providing visual explainability for clinicians using GradCAM and Attention Rollout techniques.

In this histopathology study of nevus sebaceus, researchers observed distinct epidermal, sebaceous, follicular, and apocrine changes, including sebaceous hyperplasia and basaloid adnexal proliferation, which help differentiate it from similar conditions like basal cell carcinoma and trichoblastoma.

This study reviews recent advancements in microneedles made from PLGA, highlighting their use in delivering vaccines, drugs, and proteins through the skin with minimal invasiveness, and discusses the challenges and future potential of these delivery systems.

This study found that ΔNp63α directly regulates VDR expression, which in turn may reduce invasiveness in an epidermoid cancer cell line.

In this case report, researchers diagnosed a 12-year-old girl with a nevus sebaceus of Jadassohn, characterized by a yellowish-pink plaque on the scalp and a genetic variant, following previous misdiagnosis as alopecia areata.

This report introduces a tissue-engineered nerve conduit combining hfNCSCs-derived neurons and acellular nerve grafts to potentially repair long-distance peripheral nerve injuries.

In this case study, researchers described a 47-year-old male with diabetes mellitus who developed inflammatory nevus comedonicus on his forehead, suggesting a potential link between this skin condition and diabetes. They recommend monitoring similar patients for diabetes and conducting studies to explore this association further.

A new treatment using special microneedles and a nitric oxide-releasing drug could improve hair growth and be more convenient for people with hair loss.

In this study, researchers found that niosomes, bilosomes, and spanlastic formulations can enhance the oral anticoagulation efficiency of rivaroxaban in rats, with spanlastic ranked as the most effective in prolonging clotting, prothrombin, and tail bleeding times compared to unprocessed rivaroxaban.

This review discusses prurigo nodularis and reports no new results, emphasizing the need for further research into its pathophysiology and treatment options.

In this study, a 68-year-old man with muscle-invasive bladder cancer and renal insufficiency achieved a partial radiological response to neoadjuvant therapy with gemcitabine and Disitamab Vedotin, without significant adverse events, highlighting a potential alternative for cisplatin-ineligible patients.

New microneedle method improves hair regrowth treatment delivery.

This review reports that nirmatrelvir-ritonavir has significant drug-drug interactions with many common dermatological medications, whereas molnupiravir may be an alternative therapy due to the absence of such interactions observed so far.

This case study describes a 21-year-old male diagnosed with Becker's nevus, characterized by hyperpigmented and hypertrichotic lesions that developed over several years.

This report details a case of severe recurrent bacterial vaginosis in a woman with Netherton's syndrome.