December 2024 in “International Journal of Molecular Sciences” Human umbilical cord stem cell vesicles may help treat aging and related diseases.
December 2024 in “Frontiers in Pharmacology” Araliadiol may promote hair growth like minoxidil without being toxic.
January 2024 in “Biotechnology advances” Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.
[object Object] 137 citations,
December 2007 in “Journal of bone and mineral research” Vitamin D and its receptor are crucial for bone health and can be influenced by certain fats and curcumin.
25 citations,
January 2000 in “Hormone Research in Paediatrics” Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.
60 citations,
July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
11 citations,
September 2021 in “Journal of molecular endocrinology” ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
168 citations,
August 2009 in “EMBO molecular medicine” Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
187 citations,
December 2005 in “Experimental Dermatology” Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
144 citations,
August 2019 in “Cells” The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
3 citations,
June 2023 in “Frontiers in medicine” Oxidative stress may contribute to hair loss in alopecia areata and antioxidants could potentially help as a treatment.
252 citations,
April 2009 in “Seminars in Cell & Developmental Biology” The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
48 citations,
April 2013 in “Expert Opinion on Investigational Drugs” Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.
6 citations,
May 2022 in “Aging” Si Jun Zi Tang may slow aging by affecting specific cell signaling pathways.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
February 2023 in “Asian journal of pharmaceutical research and development” Flavonoids in Iraqi marshland plants have potential health benefits like antioxidant and anti-inflammatory effects.
July 2021 in “Research Square (Research Square)” Semecarpus anacardium leaf extract fights breast cancer and extends survival in mice.
7 citations,
June 2020 in “npj regenerative medicine” GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
[object Object] 2 citations,
November 2023 in “Biomolecules” WNT signaling is crucial for skin development and healing.
1 citations,
January 2022 in “Cell Biology International” Changing CDK4 levels affects the number of stem cells in mouse hair follicles.
318 citations,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
11 citations,
October 2021 in “Frontiers in Cell and Developmental Biology” Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
72 citations,
November 2017 in “Journal of developmental biology” The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
7 citations,
January 2023 in “Journal of Hematology & Oncology” Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
7 citations,
August 2022 in “Experimental dermatology” Blocking YAP/TAZ could be a new way to treat skin cancer.
1 citations,
December 2021 in “Androgens” Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
February 2024 in “Medicina-lithuania” Obesity and bariatric surgery can cause hair thinning and temporary hair loss due to nutritional deficiencies and stress.
1 citations,
January 2019 in “Skin Pharmacology and Physiology” Eplerenone, a mineralocorticoid receptor antagonist, was found to promote hair growth in human hair follicles.
6 citations,
January 2010 in “Neoplasma” Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.
4 citations,
June 2017 in “Anais Brasileiros De Dermatologia” Aryl hydrocarbon receptor overexpression found in miniaturized hair follicles in female hair loss.