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This study in female Wistar albino rats found that Pluronic F127-stabilized nanostructured lipid carriers with tea seed or lavender oil significantly increased hair regrowth and follicular density compared to placebo, showing enhanced efficacy over a commercial product in promoting hair growth.

This study found that p2y5 functions as a novel LPA receptor involved in the G13-Rho signaling pathway, with implications for human hair growth, and proposes renaming it to LPA6.

In this study, disruptions in phospholipase A2 activity in Arabidopsis thaliana significantly impaired the plasma membrane localization of PIN proteins, affecting auxin transport and root development.

In this study, researchers developed a new Supported Ionic Liquid Phase palladium catalyst that showed effectiveness in aminocarbonylation reactions for synthesizing pharmaceutical compounds like CX-546 and a precursor of Finasteride, though results were sensitive to substrate variations and prompted palladium leaching concerns.

In this study, nanostructured lipid carriers for hair split-end repair showed similar efficacy regardless of charge, with negatively charged carriers exhibiting better stability over six months compared to positively charged ones.

This study reported that an injectable hydrogel based on platelet-rich plasma and laponite improved wound healing in diabetic and normal rats by enhancing angiogenesis and macrophage polarization.

This study reports the first identification of the deleterious NIPAL 4 variant, associated with autosomal recessive congenital ichthyosis, in an American Bully and describes its clinical management and follow-up.

This review discusses the mechanisms of platinum-induced peripheral neuropathy related to reactive oxygen species and explores potential antioxidant therapies and nanotechnology approaches, but reports no new clinical results.

This study found that NLRP1 in human melanoma cells promotes tumor growth by enhancing inflammasome activation and suppressing caspase-3 activity.

This study found that RALF peptides, through liquid-liquid phase separation, form condensates with pectin and other proteins, playing a pivotal role in plant development and stress response regulation.

In this study, the combination of Poly-D,L-Lactic Acid and Platelet-Rich Plasma was reported to be effective for improving wrinkle severity and skin brightness in a 45-year-old woman.

In this study, deleting the transcriptional pause factor Nelfb in mouse preadipocyte lineages led to defective dermal fat formation and lethal outcomes, while interventions targeting Pparg could rescue adipocyte differentiation and promote dermal white adipose tissue formation, underscoring Nelfb's critical role in adipogenesis.

This study found that nitrate, rather than ammonium, significantly enhances phosphate starvation responses in plants through a regulatory cascade involving NIGT1, SPX, and PHR1 proteins.

This study suggests that nephronectin (NPNT) could serve as a novel prognostic marker for poor prognosis in a subgroup of breast cancer patients, associated with specific NPNT staining patterns.

This phase I study reported that ETC-159, targeting Wnt signalling, showed tolerable safety profiles at doses that inhibit its pathway, though bone turnover markers increased, warranting early and regular monitoring. No tumor responses were observed, but two patients achieved stable disease for several cycles.

In this phase II clinical study, combining anlotinib with standard platinum-based chemotherapy showed promising outcomes and prognosis in treating extensive small-cell lung cancer, with high disease control and response rates.

This study found that polycaprolactone gel injections were significantly more effective than sodium hyaluronate gel in improving nasolabial fold severity for Chinese patients over 12 months, with similar rates of mild injection-related adverse events between the groups.

PLGA-based microneedles show promise for painless, long-term drug delivery but need design and safety improvements.

Phospholipid-coated nanoparticles penetrate hair follicles better than others, especially in pig ears.

This review discusses Graham-Little Piccardi-Lasseur syndrome, a rare dermatosis with limited treatment options, emphasizing the importance of early diagnosis through physical exam and dermoscopy, but reports no new results.

This study found that platelet-rich plasma may be more effective and satisfactory than topical clobetasol for treating lichen planopilaris over six months.

This review discusses lipid-polymer hybrid nanoparticles for dermatological applications, outlining their structural and formulation advancements, but reports no new clinical results and calls for further research on their therapeutic potential.

This case study reports that a 35-year-old woman developed nonscarring alopecia following the cosmetic use of poly-L-lactic acid on her face and hairline.

This study found that platelet lysate significantly improved hair growth and follicle performance in both experimental settings and AGA patients, showing results comparable to platelet-rich plasma.

In this study, the researchers compared the pharmacokinetics and tissue distribution of dihydroartemisinin in nanostructured lipid carriers versus in solution, finding longer mean residence times and variable organ accumulation with the nanostructured lipid carriers.

This study found that while epidermal PLCγ1 is not necessary for keratinocyte differentiation in interfollicular epidermis, it is crucial for normal hair and sebaceous gland formation in mice.

This study found that paclitaxel poliglumex showed limited effectiveness and was relatively well tolerated in post-menopausal women with advanced NSCLC, suggesting further testing of this treatment may not be justified.

This study reports that optimized PLA nanoparticles can effectively target hair follicles to deliver both lipophilic and hydrophilic compounds, suggesting potential applications in hair cosmetics and treatments.

The researchers reported that the facial Psoriasis Log-based Area and Severity Index (fPLASI) more reliably and sensitively captured clinical improvement in facial psoriasis than the existing facial Psoriasis Area and Severity Index (fPASI).

A 70-year-old woman with a rare skin condition improved after treatment with topical steroids and acitretin.