Search

for
Search:

Did you mean Nonmelanoma Skin Cancer?

Glossary Nonmelanoma Skin Cancer

refers to skin cancers excluding melanoma, like basal and squamous cell carcinomas

Nonmelanoma Skin Cancer (NMSC) refers to a group of skin cancers that are not melanoma, the most common types being basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). These cancers typically develop in the outer layer of the skin (epidermis) and are usually caused by prolonged exposure to ultraviolet (UV) radiation from the sun or tanning beds. While NMSC is generally less aggressive than melanoma and has a higher survival rate, early detection and treatment are crucial to prevent potential disfigurement and complications.

Sort by

Research

30 / 1000+ results

research Characteristics of non‐melanoma skin cancers of the cutaneous perioral and vermilion lip treated by Mohs micrographic surgery

8 citations , October 2018 in “Journal of the European Academy of Dermatology and Venereology”

This study found that basal cell carcinoma is more prevalent on the cutaneous lip while squamous cell carcinoma is more common on the vermilion lip, with rare recurrences following Mohs micrographic surgery.

research 014 Non-melanoma skin cancer in skin of color: Cases of mistaken identity

September 2017 in “Journal of Investigative Dermatology Symposium Proceedings”

This report highlights four cases where squamous cell carcinoma was misdiagnosed in individuals with darker skin, emphasizing the challenges in accurate diagnosis for this population.

research Electronic Brachytherapy for the Treatment of Nonmelanoma Skin Cancer: Results at 3 Years

September 2013 in “International journal of radiation oncology, biology, physics”

This study found that high dose rate electronic brachytherapy was effective for non-melanoma skin cancer, with no recurrences and good to excellent cosmesis up to three years post-treatment.

research Targeting nonmelanoma skin cancer using selective photothermolysis with 595 nm pulsed dye laser: Outcomes of 1080 cases

May 2017 in “Journal of The American Academy of Dermatology”

595 nm pulsed dye laser is a cost-effective treatment for nonmelanoma skin cancer with a low recurrence rate.

research Nonmelanoma skin cancer treated with electronic brachytherapy: Results at 1 year

78 citations , January 2013 in “Brachytherapy”

This study found that high-dose-rate electronic brachytherapy was effective for treating nonmelanoma skin cancer, with no recurrences and good to excellent cosmetic results at 1 year or more.

research Retinoids for Chemoprophylaxis of Nonmelanoma Skin Cancer

12 citations , January 2011 in “Dermatologic Surgery”

This entry contains only a placeholder abstract with no research findings described or summarized.

research Human Regulatory T Cells: Understanding the Role of Tregs in Select Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers

1 citations , January 2023 in “International Journal of Molecular Sciences”

This review explores the role of Tregs in autoimmune skin diseases, transplantation, and skin cancer, and discusses Tregs-based therapies' potential for treating autoimmunity without reporting new experimental results.

research Effect of Liquid Blood Concentrates on Cell Proliferation and Cell Cycle- and Apoptosis-Related Gene Expressions in Nonmelanoma Skin Cancer Cells: A Comparative In Vitro Study

December 2024 in “International Journal of Molecular Sciences”

This study observed that treating basal and squamous cell carcinoma cells with platelet-rich fibrin significantly reduced cell viability and increased apoptosis-associated gene expression, suggesting potential use as adjunctive therapy for localized nonmelanoma skin cancers.

research 874 Elevated expression of osteopontin splice variants in nonmelanoma skin cancer compared to normal skin and adult keratinocytes

April 2018 in “Journal of Investigative Dermatology”

The researchers reported that in nonmelanoma skin cancers, the expression of osteopontin splice variants is significantly higher compared to normal skin, with OPN-a elevated in basal cell carcinoma more than OPN-c.

research Stem Cells in Nonmelanoma Skin Cancer

January 2004

This review discusses the clonal or polyclonal nature of skin carcinomas and the stem cell origins of basal and squamous cell carcinomas but presents no new research findings.

research Association of Hypothyroidism With Nonmelanoma Skin Cancer in the Multiethnic Cohort Population-Based Study

September 2018 in “Dermatologic Surgery”

This journal exclusively publishes detailed, peer-reviewed content on dermatologic surgery but reports no new clinical results itself.

research Association of melanoma and nonmelanoma skin cancer with antihypertensive drugs: A report from the Research on Adverse Drug events And Reports project

1 citations , April 2016 in “Journal of The American Academy of Dermatology”

Blood pressure medications may increase the risk of skin cancer.

research Defining and targeting differentiation of non-melanoma skin cancer

June 2014

This study found that basal cell carcinoma exhibits patterns of hair follicle differentiation but is stuck in telogen arrest, which can be rescued by adding noggin and TGF-β2 in vitro.

research Rothmund Thomson syndrome with late onset and good preventive control of non-melanoma cancer with acitretin: case report

August 2024 in “Journal of Dermatology & Cosmetology”

This case study reports a patient with Rothmund-Thomson syndrome manifesting later in life, who was treated with acitretin to prevent non-melanoma skin cancer associated with the condition.

research Prevalence and associated factors of skin cancer in aged nursing home residents: A multicenter prevalence study

14 citations , April 2019 in “PLOS ONE”

This study found non-melanoma skin cancer in 7.2% of elderly residents in long-term care facilities in Berlin, highlighting the need for more routine skin cancer screenings in these settings.

research Usefulness of Dermoscopy to Provide Accurate Assessment of Skin Cancers

3 citations , June 2021 in “Clinical, Cosmetic and Investigational Dermatology”

This study highlights the importance of dermoscopic examinations in accurately diagnosing skin cancer, which can be mistaken for benign seborrheic keratosis, emphasizing the need for trained interpretation to avoid missing malignant lesions.

research Pre‐clinical evidences for the efficacy of tryptanthrin as a potent suppressor of skin cancer

36 citations , October 2019 in “Cell Proliferation”

This study reported that tryptanthrin, a compound found in indigo naturalis, effectively suppresses non-melanoma skin cancer in mice by reducing inflammation, inhibiting cell proliferation, and blocking specific signaling pathways associated with tumor growth.

research Targeting the Hippo/YAP/TAZ signalling pathway: Novel opportunities for therapeutic interventions into skin cancers

7 citations , August 2022 in “Experimental dermatology”

This review discusses the role of YAP/TAZ proteins in skin cancer physiology and tumorigenesis, and the potential of targeting these proteins in skin cancer treatments, but presents no new experimental findings.

research H11 More cancer, better counting or better at diagnosis? The history of skin cancer registration

June 2023 in “British Journal of Dermatology”

This study examines the historical and current development of cancer registries, highlighting their pivotal role in understanding and managing skin cancer, particularly noting improvements in the data quality of nonmelanoma skin cancers since 2013.

research What is it about your skin cancer that bothers you the most? 700 patients respond

May 2014 in “Journal of The American Academy of Dermatology”

Patients with nonmelanoma skin cancers are most bothered by fear of progression, appearance concerns, and having cancer.

research Estrogens and aging skin

150 citations , April 2013 in “Dermato-endocrinology”

This review discusses the effects of estrogen on skin aging and highlights potential therapies, but reports no new clinical findings.

research Clinical, Dermoscopic, and Histological Characteristics of Melanoma Patients According to the Age Groups: A Retrospective Observational Study

June 2023 in “Life”

In this study, researchers found that melanoma risk factors and characteristics vary with age, noting distinct differences in younger, middle-aged, and older patients, with strong correlations in the oldest group.

research Skin health of community-living older people: a scoping review

12 citations , June 2024 in “Archives of Dermatological Research”

This scoping review found a high prevalence of skin conditions among older people living at home, but available evidence on burden and effective care strategies is limited.

research Cancer risk in patients with alopecia areata: a nationwide population‐based matched cohort study

15 citations , March 2018 in “Cancer Medicine”

This study found that alopecia areata patients had a slightly decreased overall cancer risk, with significantly lower risks for some cancers but higher risks for lymphoma, breast, kidney, and urinary bladder cancers.

research Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle

5 citations , January 2016 in “Stem Cells International”

This study found that epidermal stem cells in nonglabrous skin are connected to the distal end of the arrector pili muscle, which may play a role in epidermal renewal and wound healing.

research Skin Stem Cells: At the Frontier Between the Laboratory and Clinical Practice. Part 1: Epidermal Stem Cells

2 citations , November 2015 in “Actas Dermo-Sifiliográficas”

This review discusses the characteristics and potential applications of epidermal stem cells in dermatology, without providing new clinical results.

research Data from Elevated Cutaneous Smad Activation Associates with Enhanced Skin Tumor Susceptibility in Organ Transplant Recipients

March 2023

This study found significantly higher P-Smad2 levels in both lesional and nonlesional skin of organ transplant recipients, suggesting elevated TGF-β signaling might contribute to their increased cancer susceptibility.

research Beta Human Papillomavirus and Merkel Cell Polyomavirus in Skin Neoplasms

2 citations , April 2020 in “International Journal of Dermatology and Venereology”

This review summarizes current evidence on how beta-human papillomavirus and Merkel cell polyomavirus may contribute to the development of nonmelanoma and Merkel cell skin carcinomas, respectively, but it reports no new clinical findings.

research Genome-wide association study of skin complex diseases

25 citations , March 2012 in “Journal of Dermatological Science”

This review discusses genome-wide association studies in dermatology, noting that variants linked to risk for 10 skin complex diseases have been identified, with potential implications for diagnostics and management; it reports no new clinical results.

research Review article: dermatological complications of immunosuppressive and anti-TNF therapy in inflammatory bowel disease

60 citations , September 2013 in “Alimentary Pharmacology & Therapeutics”

This review discusses the dermatological adverse events from immunosuppressive and anti-TNF therapy in IBD, finding increased risks of non-melanoma skin cancer and other skin conditions, and recommends regular cancer screening.