Electronic Brachytherapy for the Treatment of Nonmelanoma Skin Cancer: Results at 3 Years
September 2013
in “
International journal of radiation oncology, biology, physics
”
TLDR High dose rate electronic brachytherapy is an effective and safe non-surgical treatment for nonmelanoma skin cancer with good cosmetic results after three years.
The study assessed the effectiveness, adverse effects, and cosmesis of high dose rate (HDR) electronic brachytherapy for non-melanoma skin cancer (NMSC) in 172 patients with 247 lesions over three years. The treatment involved delivering 40 Gy in eight fractions using a surface applicator. No recurrences were observed with a mean follow-up of 10 months. Acute effects like rash and pruritis were common but resolved within a year, while late effects included hypopigmentation and hair loss. Cosmesis was rated as good to excellent in all cases up to three years post-treatment. The study concluded that HDR electronic brachytherapy is an effective, non-surgical treatment option for NMSC with acceptable toxicity and excellent cosmetic outcomes.