Scalp-Sparing Total Skin Electron Therapy in Mycosis Fungoides: Case Report Highlighting Technique and Outcome

    March 2016 in “ Practical radiation oncology ”
    Noelle L. Williams, James Keller, E Kremmel, Virginia Lockamy, A Harrison, Wenyin Shi
    TLDR Total skin electron therapy is an effective treatment for mycosis fungoides, balancing effectiveness and side effects.
    The document discussed a case report on scalp-sparing total skin electron therapy (TSET) for treating mycosis fungoides (MF), the most common cutaneous T-cell lymphoma. Historically, TSET showed improved complete response rates with dose escalation from 8 Gy to 36 Gy, but this also increased toxicity, including dry desquamation, skin erythema, alopecia, anhidrosis, and loss of fingernails. Recent studies have focused on dose de-escalation to reduce these toxicities while maintaining response rates. The case report highlighted the technique and outcomes of using a scalp-sparing approach in TSET.
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