Folliculotropic Mycosis Fungoides Complicated by Eosinophilia: A Case Report

    September 2011 in “ Chinese Journal of Dermatology
    Jun Song, Zhouwei Wu, Yue Sun, Guang-dou Zhu, Weimin Shi
    TLDR A man's skin condition was misdiagnosed and later identified as a rare type of skin cancer, which did not improve with treatment.
    A 69-year-old man with a 3-year history of skin issues, including erythematous patches, perifollicular papules, acneiform lesions, alopecia, and peripheral eosinophilia, was initially misdiagnosed with folliculitis. Despite initial treatment with antihistamines and antibiotics, his condition progressed, leading to a diagnosis of folliculotropic mycosis fungoides after further histopathological and immunohistochemical examinations. The tests revealed dense dermal infiltrates of lymphoid cells and eosinophils, and positive staining for several markers, but negative for others, including T-cell receptor gene rearrangement. Treatment with photochemotherapy and acitretin did not prevent the emergence of new skin lesions, and the patient continued to be monitored.
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