March 2014 in “Human Physiology” DHEA improved brain function and behavior in old monkeys and had additional health benefits.
19 citations,
December 2013 in “European journal of pharmaceutics and biopharmaceutics” Encapsulated Garcinia mangostana extract in cream penetrates skin better than other forms.
14 citations,
January 2020 in “Biomaterials Science” Created microspheres show potential for safe and effective use in prostate artery embolization.
12 citations,
April 2018 in “Physiology & Behavior” Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.
June 2022 in “International journal of drug delivery technology” Nebivolol cream may be a promising hair loss treatment by improving blood flow and nourishing hair follicles.
52 citations,
January 2013 in “Journal of Dermatological Science” The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
26 citations,
September 2011 in “International Journal of Pharmaceutics” SLN suspensions work as well as commercial solutions for minoxidil delivery, but are non-corrosive, making them a promising alternative.
276 citations,
April 2018 in “Journal of Dermatological Science” The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
7 citations,
February 2015 in “Journal of comparative pathology” CD8+ T cells play a key role in graft-versus-host disease in certain mice models.
July 2011 in “Springer eBooks” The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.
16 citations,
June 2017 in “Advances in Therapy” New treatments for hair loss are showing promise due to better understanding of genetics and the immune system.
August 2024 in “Current Protocols” The C3H/HeJ mouse model is useful for studying and testing treatments for alopecia areata.
81 citations,
February 2016 in “Veterinary pathology” Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
11 citations,
December 2018 in “Journal of the European Academy of Dermatology and Venereology” Stopping JAK inhibitor treatment for hair loss can lead to worse hair loss than before the treatment.
3 citations,
January 2020 in “Plastic and Aesthetic Research” Non-surgical procedures can help reduce wrinkles and stimulate skin repair by understanding skin aging at the molecular level.
September 2023 in “Biomedical Optics Express” New imaging techniques show testosterone delays hair growth and shrinks follicles in mice, but have limited depth for viewing.
421 citations,
January 2015 in “Chemical Society Reviews” Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.
204 citations,
February 2000 in “Current Medicinal Chemistry” Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
147 citations,
November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
129 citations,
November 2005 in “Internal Medicine Journal” Early detection and intensive treatment of diseases caused by Staphylococcus aureus toxins are crucial for reducing severe health effects.
65 citations,
August 2013 in “Tissue Engineering Part B-reviews” Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
62 citations,
August 2018 in “Frontiers in Endocrinology” Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
47 citations,
November 2012 in “Expert Opinion on Therapeutic Patents” The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
29 citations,
September 2012 in “Birth Defects Research” Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.
28 citations,
December 2012 in “The American Journal of Cosmetic Surgery” Proteins from stem cells improved hair growth in patients with hair loss.
24 citations,
March 2019 in “Life sciences” Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
21 citations,
October 2009 in “Biochemical Engineering Journal” Stem cell therapy is a promising approach for hair regrowth despite potential side effects.
17 citations,
June 2021 in “Molecules” Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.
16 citations,
November 2021 in “Antioxidants” Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.
15 citations,
March 2014 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” ACBP is essential for healthy skin and fur by maintaining the skin's barrier function.