research COVID-19, Androgens, and Androgenic Alopecia
COVID-19 may worsen with androgens; anti-androgen drugs could help.
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research Crystal Structure and Synthesis of 17α-Hexanoyloxy-16β-Methylpregna-4,6-Diene-3,20-Dione
A new compound that could treat various androgen-related conditions was created and analyzed.
research Crystal Structure and Synthesis of 17α-Acetoxy-Pregn-4,6-Diene-3,20-Dione
The compound was successfully made and shows potential for treating prostate cancer.
research Analysis of Female Pattern Hair Loss
Early treatment of Female Pattern Hair Loss is important to stop it from getting worse, and various treatments can help, especially in mild to moderate cases.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research Current Concepts in Aesthetic Endocrinology
Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.
research Increased Risk of Fractures in Patients with Polycystic Ovary Syndrome: A Nationwide Population-Based Retrospective Cohort Study
Women with polycystic ovary syndrome have a higher risk of certain fractures.
research Hormonal Prevention of Prostate Cancer
Suppressing certain hormones might help prevent prostate cancer.
research Prostate-Specific Antigen as a Diagnostic Marker in Female Hyperandrogenism
PSA could be a marker for hyperandrogenism in women, but more research is needed.
research Cyproterone Acetate: A Genotoxic Carcinogen?
Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.
research Tributyltin Effects on Ocinebrina Aciculata: Imposex Development, Sterilization, Sex Change, and Population Decline
Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.
research The Effect of 5-Reductase Inhibitors on Erectile Function
5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Finasteride-Induced Inhibition of 5α-Reductase Type 2 Could Lead to Kidney Damage: An Experimental Animal Study
Finasteride may cause kidney damage.
research Evaluation of Hair Growth Activity of Buxus Wallichiana Baill Extract in Rats
Buxus wallichiana extract improves hair growth and has antioxidant properties, with oral use more effective than topical.
research A Clinical Study of the Effects of Finasteride on Androgenetic Alopecia
Finasteride effectively treats hair loss in men with minimal side effects.
research Finasteride in the Treatment of Men with Androgenetic Alopecia
Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.
research External Genitalia Abnormalities in Male Rats Exposed In Utero to Finasteride, a 5α-Reductase Inhibitor
Finasteride exposure in pregnancy causes genital abnormalities in male rats.
research Liposomes in Cosmeceuticals
Liposomes could improve how skin care products work but are costly and not very stable.
research Development and Homeostasis of the Sebaceous Gland
The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
research Congenital Adrenal Hyperplasia: A Comprehensive Review
The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.
research Inhibitors of 5α-Reductase in the Treatment of Benign Prostatic Hyperplasia
5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.
research Effects of Ginseng Rhizome and Ginsenoside Ro on Testosterone 5α-Reductase and Hair Regrowth in Testosterone-Treated Mice
Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.
research Hair Growth: Focus on Herbal Therapeutic Agents
Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.
research Finasteride, a Type 2 5α-Reductase Inhibitor, in the Treatment of Men with Androgenetic Alopecia
Finasteride effectively treats male hair loss, improving growth and density.
research Male Hormonal Contraception: Looking Back and Moving Forward
New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.
research Spironolactone and XPB: An Old Drug with a New Molecular Target
Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
research Exposure of Xenopus Laevis Tadpoles to Finasteride, an Inhibitor of 5-Alpha Reductase Activity, Impairs Spermatogenesis and Alters Hypophyseal Feedback Mechanisms
Finasteride exposure harms tadpole reproduction and hormone balance.
research Current and Emerging Treatment Strategies for Hair Loss in Women of Color
Early treatment helps stop hair loss in women of color.
research Early Embryonic Exposure of Freshwater Gastropods to Pharmaceutical 5-Alpha-Reductase Inhibitors Results in a Surprising Open-Coiled 'Banana-Shaped' Shell
Certain drugs change freshwater snail shells to a "banana" shape.