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Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Microneedling is a safe and effective treatment for various skin conditions, often preferred for its fewer side effects and shorter recovery time.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.

BMP2 and BMP7 have opposite roles in feather formation.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Alopecia areata involves immune system imbalances that may lead to depression and anxiety.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.

Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Dupilumab may cause significant hair loss, which can reverse after stopping the drug.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.