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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Noggin is necessary to start the hair growth phase in skin after birth.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Finasteride effectively treats baldness but may cause sexual side effects.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Hair loss linked to higher heart disease risk in both men and women.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.